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Merck
CN

27690

2,4,6-Trimethylpyridine

99% (GC), liquid, puriss. p.a.

Synonym(s):

2,4,6-Collidine, sym-Collidine

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About This Item

Empirical Formula (Hill Notation):
C8H11N
CAS Number:
Molecular Weight:
121.18
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
203-613-3
MDL number:
Beilstein/REAXYS Number:
107283
Assay:
99% (GC)
Form:
liquid
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Product Name

2,4,6-Trimethylpyridine, puriss. p.a., 99% (GC)

grade

puriss. p.a.

Quality Level

assay

99% (GC)

form

liquid

impurities

≤0.1% water

evapn. residue

≤0.1%

refractive index

n20/D 1.498

bp

171-172 °C (lit.)

mp

−43 °C (lit.)

density

0.917 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.5 mg/kg, Ba: ≤0.1 mg/kg, Bi: ≤0.1 mg/kg, Ca: ≤0.5 mg/kg, Cd: ≤0.05 mg/kg, Co: ≤0.02 mg/kg, Cr: ≤0.02 mg/kg, Cu: ≤0.02 mg/kg, Fe: ≤0.1 mg/kg, K: ≤0.5 mg/kg, Li: ≤0.1 mg/kg, Mg: ≤0.1 mg/kg, Mn: ≤0.02 mg/kg, Mo: ≤0.1 mg/kg, Na: ≤0.5 mg/kg, Ni: ≤0.02 mg/kg, Pb: ≤0.1 mg/kg, Sr: ≤0.1 mg/kg, Zn: ≤0.1 mg/kg

storage temp.

2-8°C

SMILES string

Cc1cc(C)nc(C)c1

InChI

1S/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3

InChI key

BWZVCCNYKMEVEX-UHFFFAOYSA-N

General description

2,4,6-Trimethylpyridine is a heterocyclic aromatic compound that is commonly used in dehydrohalogenation reactions. It is also used as a reaction solvent or chemical additive in organic reactions due to its basic properties.

Application

2,4,6-Trimethylpyridine can be used as a reagent:      
  • In solid-phase peptide synthesis.     
  • To synthesize trichloro(2,4,6-trimethylpyridine) Au(III) complex by reacting with HAuCl4.

Tissue fixative for electron microscopy.


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pictograms

FlameSkull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

131.0 °F - closed cup

flash_point_c

55 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

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Assessing the acid properties of desilicated ZSM-5 by FTIR using CO and 2, 4, 6-trimethylpyridine (collidine) as molecular probes.
Holm MS, et al.
Applied Catalysis A: General, 356(1), 23-30 (2009)
J L Tomsig et al.
Histochemistry, 89(3), 301-306 (1988-01-01)
In previous work of our laboratory it was demonstrated that collidine (2,4,6-trimethylpyridine) abolishes the core osmiophilia and chromaffin reaction from rat pinal gland and vas deferens nerves. This abolition was apparent when tissues were briefly incubated in collidine or when
Leszek Pazderski et al.
Magnetic resonance in chemistry : MRC, 48(6), 417-426 (2010-05-18)
(1)H, (13)C and (15)N NMR studies of gold(III), palladium(II) and platinum(II) chloride complexes with dimethylpyridines (lutidines: 2,3-lutidine, 2,3lut; 2,4-lutidine, 2,4lut; 3,5-lutidine, 3,5lut; 2,6-lutidine, 2,6lut) and 2,4,6-trimethylpyridine (2,4,6-collidine, 2,4,6col) having general formulae [AuLCl(3)], trans-[PdL(2)Cl(2)] and trans-/cis-[PtL(2)Cl(2)] were performed and the respective



Global Trade Item Number

SKUGTIN
27690-100ML04061826187630
27690-500ML04061838135193