27963
Castor Oil, Ethoxylated
Synonym(s):
Cremophor® EL, EL, Macrogolglycerol ricinoleate, PEG-35 castor oil, Polyoxyl-35 castor oil
InChI
1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)
InChI key
JMNCUXPHXKHBPY-UHFFFAOYSA-N
description
non-ionic
density
1.05 g/mL at 20 °C
application(s)
sample preservation
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Other Notes
A derivative of castor oil and ethylene oxide.
This product has been replaced by C5135-SIGMA | Kolliphor EL pH-range 6.0 - 8.0
Legal Information
Cremophor is a registered trademark of BASF SE
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
494.6 °F - Not applicable
flash_point_c
257 °C - Not applicable
ppe
Eyeshields, Gloves
Regulatory Information
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N Venkatesan et al.
Journal of controlled release : official journal of the Controlled Release Society, 111(1-2), 19-26 (2005-12-27)
The absorption of erythropoietin (EPO) from rat small intestine was studied using gastro-intestinal patches (GI-PS) in the presence of absorption enhancers. Surfactants such as a saturated polyglycolysed C8-C18 glyceride (Gelucire 44/14), PEG-8 capryl/caprylic acid glycerides (Labrasol), and polyoxyethylene hydrogenated castor
Kumiko Ueda et al.
Journal of drug targeting, 11(1), 37-43 (2003-07-11)
Lipid emulsions with particle sizes of 190-270 nm were prepared with soybean oil (SO) and a series of hydrogenated castor oils (HCOs) with various oxyethylene numbers, and the effect of oxyethylene numbers of HCOs on the pharmacokinetics of menatetrenone incorporated
Hong-Tao Song et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 31(17), 1413-1417 (2006-11-08)
To prepare a sustained-release formulation of traditional Chinese medicine compound recipe by adopting time-controlled release techniques. Shuxiong tablets were chosen as model drug. The prescription and technique of core tablets were formulated with selecting disintegrating time and swelling volume of
Ming-Kung Yeh et al.
AAPS PharmSciTech, 10(1), 166-171 (2009-02-19)
The formulation study of tenoxicam, a poorly water-soluble drug, was developed by use of a ternary cosolvent system and has significantly enhanced the solubility. Additionally, the relative bioavailability of testing formulation was also evaluated by New Zealand rabbit with a
Jessica M Jones et al.
eLife, 9 (2020-08-08)
Objective and automatic measurement of pain in mice remains a barrier for discovery in neuroscience. Here, we capture paw kinematics during pain behavior in mice with high-speed videography and automated paw tracking with machine and deep learning approaches. Our statistical
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