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Merck
CN

28244

Sigma-Aldrich

Ethyl cellulose

tested according to Ph. Eur., viscosity 10 mPa.s 

Synonym(s):

Ethylcellulosum

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About This Item

CAS Number:
9004-57-3
MDL number:
MFCD00131037
UNSPSC Code:
12352200

Key Documents

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Agency

USP/NF
tested according to Ph. Eur.

form

coarse powder

autoignition temp.

698 °F

concentration

48.0-49.5% (Ethoxy (OC2H5) groups (dried substances)- EU Portal, GC)

refractive index

n20/D 1.47 (lit.)

viscosity

10 mPa.s

solubility

acetone: soluble
benzene: soluble
butyl acetate: soluble
carbon tetrachloride: soluble
ethanol: soluble
glycerol: insoluble
propylene glycol: insoluble
water: insoluble
xylene: soluble

density

1.14 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

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General description

Ethyl cellulose is a lipophilic polymer that possesses excellent membrane-forming ability and durability. It facilitates the formation of free films and is utilized in studying the dynamic interaction of polymer films with water.

Application

Ethyl cellulose has been used in the preparation of biostructures such as matrices, microspheres, microparticles, pellets and tablets for use in drug delivery. It has also been used in making chemically modified ethyl cellulose-based membrane for the purification of IgG.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBQ4872V

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A Martinac et al.
International journal of pharmaceutics, 291(1-2), 69-77 (2005-02-15)
Loratadine-loaded microspheres were prepared by spray-drying of dispersions, emulsions and suspensions differing in polymeric composition and solvents used. Conventional microspheres were obtained by spray-drying of dispersions composed of chitosan (CM) as only polymer, while composed microspheres were obtained by spray-drying
Anna Jansson et al.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, 20(2), 394-406 (2014-02-26)
Drug release from oral pharmaceutical formulations can be modified by applying a polymeric coating film with controlled mass transport properties. Interaction of the coating film with water may crucially influence its composition and permeability to both water and drug. Understanding
Anurag Verma et al.
Acta pharmaceutica (Zagreb, Croatia), 62(2), 237-250 (2012-07-04)
Chitosan has become a focus of major interest in recent years due to its excellent biocompatibility, biodegradability and non-toxicity. Although this material has already been extensively investigated in the design of different types of drug delivery systems, it is still
Daniela Traini et al.
International journal of pharmaceutics, 438(1-2), 150-159 (2012-09-12)
The potential of excipient coating to enhance aerosol performance of micronized drugs in carrier excipient-drug blends, used in dry powder inhalers, was investigated. Both EC (ethyl cellulose) and PVP (polyvinylpyrrolidone) were used as coating agents. Carriers were prepared via sieve
Syed Umer Jan et al.
Pakistan journal of pharmaceutical sciences, 25(4), 751-756 (2012-09-27)
The aim and objective of the present study was to formulate and evaluate controlled release polymeric tablets of ibuprofen with determinations of formulation factors using various grades and types of polymer ethocel i.e. ethocel standard 10P; 10FP, 100P and100FP for
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