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Merck
CN

28730

Cyclododecanone

purum, ≥99.0% (GC)

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About This Item

Linear Formula:
C12H22(=O)
CAS Number:
Molecular Weight:
182.30
EC Number:
212-595-6
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
508621
MDL number:
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grade

purum

assay

≥99.0% (GC)

bp

85 °C/1 mmHg (lit.)

mp

59-61 °C

density

0.906 g/mL at 25 °C (lit.)

SMILES string

O=C1CCCCCCCCCCC1

InChI

1S/C12H22O/c13-12-10-8-6-4-2-1-3-5-7-9-11-12/h1-11H2

InChI key

SXVPOSFURRDKBO-UHFFFAOYSA-N

General description

The expediancy of the bioproduction of lauryl lactone from cyclododecanone was examined.

Application

Cyclododecanone was used in the synthesis of novel macrocyclic molecules comprising sulfonyl and acyl moiety at the position N-12a of 16-membered azalides and azalactams scaffold.

Regulatory Information

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Xiaolei Wang et al.
European journal of medicinal chemistry, 73, 286-294 (2014-01-29)
Novel macrocyclic molecules comprising sulfonyl and acyl moiety at the position N-12a of 16-membered azalides (6a-n) and azalactams (10a-r) scaffold were synthesized from cyclododecanone 1 as starting material via 5 steps and 4 steps, respectively. The antifungal activity of these
Jianzhong Yang et al.
Applied microbiology and biotechnology, 84(5), 867-876 (2009-05-16)
Recombinant Escherichia coli whole-cell biocatalysts harboring either a Baeyer-Villiger monooxygenase or ferulic acid decarboxylase were employed in organic-aqueous two-phase bioreactor systems. The feasibility of the bioproduction of water-insoluble products, viz., lauryl lactone from cyclododecanone and 4-vinyl guaiacol from ferulic acid

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