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About This Item
Linear Formula:
(CH3)3N+CH2COO-
CAS Number:
Molecular Weight:
117.15
EC Number:
203-490-6
UNSPSC Code:
41116107
PubChem Substance ID:
Beilstein/REAXYS Number:
3537113
MDL number:
product line
TraceCERT®
grade
certified reference material, TraceCERT®
shelf life
limited shelf life, expiry date on the label
analyte chemical class(es)
amino acids, peptides, proteins
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
SMILES string
C[N+](C)(C)CC([O-])=O
InChI
1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
InChI key
KWIUHFFTVRNATP-UHFFFAOYSA-N
General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034 (ISO Guide 34). This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Legal Information
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Mahmoud S Khaniani et al.
Molecular cytogenetics, 1, 5-5 (2008-05-13)
Fragile X syndrome (OMIM #300624) is the most common, recognised, heritable cause of mental retardation. Widespread testing is warranted by the relatively high frequency of the disorder, the benefits of early detection and the identification of related carriers whose offspring
Per Magne Ueland
Journal of inherited metabolic disease, 34(1), 3-15 (2010-05-07)
Choline is an essential nutrient, but is also formed by de novo synthesis. Choline and its derivatives serve as components of structural lipoproteins, blood and membrane lipids, and as a precursor of the neurotransmitter acetylcholine. Pre-and postnatal choline availability is
Bernd C Schwahn et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(3), 512-514 (2003-01-29)
Hyperhomocysteinemia, a proposed risk factor for cardiovascular disease, is also observed in other common disorders. The most frequent genetic cause of hyperhomocysteinemia is a mutated methylenetetrahydrofolate reductase (MTHFR), predominantly when folate status is impaired. MTHFR synthesizes a major methyl donor