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Merck
CN

30420

Phosphinic acid

puriss. p.a., 49.5-50.5% (alkalimetric)

Synonym(s):

Hypophosphorous acid

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About This Item

Linear Formula:
H3PO2
CAS Number:
Molecular Weight:
66.00
UNSPSC Code:
12352106
PubChem Substance ID:
EC Number:
228-601-5
MDL number:
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grade

puriss. p.a.

concentration

49.5-50.5% (alkalimetric)

impurities

≤0.001% heavy metals (as Pb), ≤0.02% total S (as SO4)

density

1.206 g/mL at 20 °C (lit.)

anion traces

chloride (Cl-): ≤150 mg/kg, phosphate, phosphite (as H3PO3): ≤1%

cation traces

As: ≤2 mg/kg, Ba: ≤50 mg/kg, Ca: ≤50 mg/kg, Cd: ≤1 mg/kg, Cu: ≤1 mg/kg, Fe: ≤10 mg/kg, K: ≤10 mg/kg, Mn: ≤5 mg/kg, Na: ≤60 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤1 mg/kg

SMILES string

O[PH2]=O

InChI

1S/H3O2P/c1-3-2/h3H2,(H,1,2)

InChI key

ACVYVLVWPXVTIT-UHFFFAOYSA-N



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Preparation of phosphinic acids: Michael additions of phosphonous acids/esters to conjugated systems.
Thottathil JK, et al.
Tetrahedron Letters, 25(42), 4741-4744 (1984)
William W Metcalf et al.
Annual review of biochemistry, 78, 65-94 (2009-06-06)
Natural products containing carbon-phosphorus bonds (phosphonic and phosphinic acids) have found widespread use in medicine and agriculture. Recent years have seen a renewed interest in the biochemistry and biology of these compounds with the cloning of the biosynthetic gene clusters
The invention of radical reactions. Part 32. Radical deoxygenations, dehalogenations, and deaminations with dialkyl phosphites and hypophosphorous acid as hydrogen sources.
Barton DHR, et al.
The Journal of Organic Chemistry, 58(24), 6838-6842 (1993)