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Merck
CN

30494

Silydianin

analytical standard

Synonym(s):

Silidianin

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About This Item

Empirical Formula (Hill Notation):
C25H22O10
CAS Number:
Molecular Weight:
482.44
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
EC Number:
249-848-5
MDL number:
Technical Service
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grade

analytical standard

Quality Level

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤10.0% residual solvents (GC-HS), ≤10.0% water

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

COc1cc(ccc1O)[C@@H]2[C@H]3CO[C@]4(O)[C@H]3C(=C[C@H]2C4=O)[C@H]5Oc6cc(O)cc(O)c6C(=O)[C@@H]5O

InChI

1S/C25H22O10/c1-33-16-4-9(2-3-14(16)27)18-11-7-12(20-13(18)8-34-25(20,32)24(11)31)23-22(30)21(29)19-15(28)5-10(26)6-17(19)35-23/h2-7,11,13,18,20,22-23,26-28,30,32H,8H2,1H3/t11-,13-,18+,20+,22+,23-,25-/m1/s1

InChI key

CYGIJEJDYJOUAN-JSGXPVSSSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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János Fehér et al.
Orvosi hetilap, 149(51), 2413-2418 (2008-12-17)
In the treatment of chronic liver diseases adequate therapy can be chosen only in the knowledge of pathogenetic processes. In the liver diseases caused by oxidative stress (alcoholic and non-alcoholic fatty liver and steatohepatitis, drug and compound induced liver toxicity)
Silybin and silydianin diminish the oxidative metabolism of human polymorphonuclear neutrophils.
E Ignatowicz et al.
Acta biochimica Polonica, 44(1), 127-129 (1997-01-01)
Małgorzata Zielińska-Przyjemska et al.
Phytotherapy research : PTR, 20(2), 115-119 (2006-01-31)
The inhibitory effect of silydianin, an active constituent of Silybium marianum, on the in vitro production and release of oxidative products has been examined. Polymorphonuclear neutrophils (PMNs) play a primary role in the initiation and propagation of inflammatory responses. Their



Global Trade Item Number

SKUGTIN
30494-10MG04061834111894