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Merck
CN

30553

Samarium(III) ionophore I

Selectophore™

Synonym(s):

Glipizide, 1-Cyclohexyl-3-{4-[2-(5-methylpyrazine-2-carboxamido)ethyl]phenylsulfonyl}urea

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About This Item

Empirical Formula (Hill Notation):
C21H27N5O4S
CAS Number:
29094-61-9
Molecular Weight:
445.54
UNSPSC Code:
26111700
PubChem Substance ID:
24858438
EC Number:
249-427-6
MDL number:
MFCD00072159

Key Documents

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InChI key

ZJJXGWJIGJFDTL-UHFFFAOYSA-N

InChI

1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)

SMILES string

Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3

product line

Selectophore™

General description

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Other Notes

Indicator electrode for the potentiometric determination of Sm(III) with EDTA

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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M.R. Ganjali et al.
Sensors and Actuators B, Chemical, 89, 21-21 (2003)
D F Pereira et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(10), 868-877 (2012-07-17)
In this study we examined the acute in vivo effect and short- and long-term in vitro effects of samples from native and commercial Ilex paraguariensis on glucose homeostasis. Also, the potential effect of I. paraguariensis on serum insulin secretion was
Karl J Krobot et al.
Current medical research and opinion, 28(8), 1281-1287 (2012-06-16)
In a previously-published study, adding sitagliptin or glipizide to ongoing metformin therapy provided similar HbA(1c) improvement (both groups, -0.7%) after 52 weeks in patients with type 2 diabetes (T2DM). Significantly fewer patients experienced symptomatic hypoglycemia with sitagliptin (5% of 588
Ning Li et al.
Biomedical chromatography : BMC, 27(2), 191-196 (2012-07-06)
A selective, sensitive and rapid high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was developed and validated to determine metformin and glipizide simultaneously in human plasma using phenacetin as internal standard (IS). After one-step protein precipitation of 200 μL plasma with
K M Pantalone et al.
Diabetic medicine : a journal of the British Diabetic Association, 29(8), 1029-1035 (2012-01-18)
Sulfonylureas have been shown to increase mortality when used in combination with metformin. This may not be a class effect of sulfonylureas, but rather secondary to differences in properties inherent to the individual sulfonylureas (hypoglycaemic risk, sulfonylurea receptor selectivity and
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