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Merck
CN

30908

Sigma-Aldrich

Cap A (acetic anhydride 10% in THF)

suitable for DNA synthesis

Synonym(s):

Acetic anhydride solution

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352100
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technique(s)

DNA synthesis: suitable

impurities

≤0.01% water

density

0.906 g/mL at 20 °C

SMILES string

CC(=O)OC(C)=O

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Application

Reagent used in the phosphite triester method of oligonucleotide synthesis for the capping of the remaining free 5′-hydroxyl groups by acetylation. Reagent is suitable for use on Biosearch 8000, Expedite, Cyclone synthesizers.

Preparation Note

filtered with a 0.1 μm filter

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-0.4 °F

Flash Point(C)

-18 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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