310441
Lead(II) chromate
ACS reagent, ≥98.0%
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About This Item
Linear Formula:
PbCrO4
CAS Number:
Molecular Weight:
323.19
EC Number:
231-846-0
UNSPSC Code:
12352300
MDL number:
InChI key
MOUPNEIJQCETIW-UHFFFAOYSA-N
InChI
1S/Cr.4O.Pb/q;;;2*-1;+2
SMILES string
[PbH2++].[O-][Cr]([O-])(=O)=O
grade
ACS reagent
assay
≥98.0%
impurities
≤0.01% C compounds, ≤0.15% solubles
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Carc. 1A - Repr. 1A - STOT RE 2
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
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Amie L Holmes et al.
Toxicology and applied pharmacology, 203(2), 167-176 (2005-02-16)
Hexavalent chromium (Cr (VI)) compounds are established human lung carcinogens. Solubility plays a key role in Cr (VI) carcinogenicity, with the most potent carcinogens being water-insoluble or 'particulate'. Lead chromate is used as the prototypical particulate Cr (VI) compound since
Role of the Fancg gene in protecting cells from particulate chromate-induced chromosome instability.
Laura C Savery et al.
Mutation research, 626(1-2), 120-127 (2006-11-14)
Particulate hexavalent chromium (Cr(VI)) is a known human lung carcinogen. Cr(VI)-induced tumors exhibit chromosome instability (CIN), but the mechanisms underlying these effects are unknown. We investigated a possible role for the Fanconi anemia (FA) pathway in particulate Cr(VI)-induced chromosomal damage
Stephen S Leonard et al.
Molecular and cellular biochemistry, 255(1-2), 171-179 (2004-02-20)
Exposure to certain particulate hexavalent chromium [Cr(VI)] compounds, such as lead chromate (PbCrO4), has been associated with lung cancer and respiratory tract toxicity. Previous studies indicate that the solubility of Cr(VI)-compounds is an important factor in Cr(VI)-induced carcinogenesis. The present
Megan M Stackpole et al.
Mutation research, 625(1-2), 145-154 (2007-07-31)
Particulate hexavalent chromium [Cr(VI)] compounds are well-established human carcinogens. Cr(VI)-induced tumors are characterized by chromosomal instability (CIN); however, the mechanisms of this effect are unknown. We investigated the hypothesis that homologous recombination (HR) repair of DNA double-strand breaks protect cells
Earle R Nestmann et al.
Mutation research, 633(2), 126-132 (2007-07-24)
Lead chromate pigment in the form of the commercial pigment, Pigment Yellow 34, CAS No. 1344-37-2, used in the plastics and coatings industries, did not induce chromosome aberrations in Chinese hamster ovary (CHO) cell line WB(L). Lead chromate pigment is
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