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Merck
CN

31706

Supelco

Nitrofurazone solution

VETRANAL®, 100 μg/mL in acetonitrile, analytical standard

Synonym(s):

Nitrofural solution

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About This Item

Empirical Formula (Hill Notation):
C6H6N4O4
CAS Number:
59-87-0
Molecular Weight:
198.14
Beilstein:
1347298
EC Number:
200-835-2
MDL number:
MFCD00003225
UNSPSC Code:
41116107
PubChem Substance ID:
329753890
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

SMILES string

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

InChI key

IAIWVQXQOWNYOU-FPYGCLRLSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN5410
BCCF3643
BCBT4214

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James R Johnson et al.
The Journal of urology, 184(6), 2572-2577 (2010-10-30)
We determined the activity, comparative potency and effect durability of commercially available, antimicrobial coated Foley catheters against Escherichia coli isolates, including extended spectrum cephalosporin resistant strains. We used an inhibition zone assay (diffusible inhibition) and an adherence assay (diffusible and
Ali Ryan et al.
Scientific reports, 1, 63-63 (2012-02-23)
Azoreductases are well known for azo pro-drug activation by gut flora. We show that azoreductases have a wider role in drug metabolism than previously thought as they can also reduce and hence activate nitrofurazone. Nitrofurazone, a nitroaromatic drug, is a
R Pickard et al.
Health technology assessment (Winchester, England), 16(47), 1-197 (2012-12-04)
Catheter-associated urinary tract infection (CAUTI) is a major preventable cause of harm for patients in hospital and incurs significant costs for health-care providers such as the UK NHS. Many preventative strategies and measures have been introduced to minimise CAUTI risk
Robert Pickard et al.
Lancet (London, England), 380(9857), 1927-1935 (2012-11-09)
Catheter-associated urinary tract infection (CAUTI) is a major preventable cause of harm for patients in hospital. We aimed to establish whether short-term routine use of antimicrobial catheters reduced risk of CAUTI compared with standard polytetrafluoroethylene (PTFE) catheterisation. In our parallel
Ryan W Benson et al.
PloS one, 6(5), e19944-e19944 (2011-05-27)
DinB (DNA Pol IV) is a translesion (TLS) DNA polymerase, which inserts a nucleotide opposite an otherwise replication-stalling N(2)-dG lesion in vitro, and confers resistance to nitrofurazone (NFZ), a compound that forms these lesions in vivo. DinB is also known
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