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Merck
CN

31706

Nitrofurazone solution

100 μg/mL in acetonitrile, VETRANAL®, analytical standard

Synonym(s):

Nitrofural solution

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About This Item

Empirical Formula (Hill Notation):
C6H6N4O4
CAS Number:
Molecular Weight:
198.14
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-835-2
Beilstein/REAXYS Number:
1347298
MDL number:
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InChI key

IAIWVQXQOWNYOU-FPYGCLRLSA-N

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

SMILES string

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

2-8°C

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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Assessing catheter-associated urinary tract infection - Authors' reply.
Robert Pickard et al.
Lancet (London, England), 381(9877), 1536-1536 (2013-05-07)
Prevention of CAUTI: simple is beautiful.
Marc Leone
Lancet (London, England), 380(9857), 1891-1892 (2012-11-09)
Man Chin Chung et al.
Current pharmaceutical design, 17(32), 3515-3526 (2011-11-15)
In therapeutics research, the nitro compounds are part of an important group of drugs with multiple pharmacological activities. However, in drug design, the inclusion of a nitro group in a molecule changes the physico-chemical and electronic properties and is associated
James R Johnson et al.
Antimicrobial agents and chemotherapy, 56(9), 4969-4972 (2012-07-04)
Two marketed antimicrobial-coated Foley catheters were compared for in vitro diffusible and contact-dependent inhibition of 11 urinary tract infection-associated microorganisms in an adherence-biofilm assay. Nitrofurazone-coated catheters significantly outperformed silver alloy-coated catheters for inhibitory activity, according to both inoculum broth and
Fengyu Deng et al.
Molecular bioSystems, 8(5), 1446-1451 (2012-02-18)
The interaction of nitrofurazone (NF) and human serum albumin (HSA) has been studied by fluorescence spectroscopy, FT-IR spectroscopy and molecular modeling methods. The results showed that the fluorescence of HSA was quenched by NF in a static quenching mechanism. Thermodynamic

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