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Merck
CN

32154

Buparvaquone

VETRANAL®, analytical standard

Synonym(s):

2-[(4-tert-Butylcyclohexyl)methyl]-3-hydroxy-1,4-naphthoquinone, 2-[[4-(1,1-Dimethylethyl)cyclohexyl]methyl]-3-hydroxy-1,4-naphthalenedione

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About This Item

Empirical Formula (Hill Notation):
C21H26O3
CAS Number:
88426-33-9
Molecular Weight:
326.43
NACRES:
NA.24
PubChem Substance ID:
329754074
UNSPSC Code:
41116107
MDL number:
MFCD01712789

Key Documents

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Product Name

Buparvaquone, VETRANAL®, analytical standard

InChI

1S/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,24H,8-12H2,1-3H3

SMILES string

CC(C)(C)C1CCC(CC1)CC2=C(O)C(=O)c3ccccc3C2=O

InChI key

KLLIVCPQDTYMLC-UHFFFAOYSA-N

grade

analytical standard

product line

VETRANAL®

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL6451
BCCJ1444
BCCJ1032
BCCG7901
BCCB5496

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Juliana Q Reimão et al.
Experimental parasitology, 130(3), 195-199 (2012-01-28)
The objective of this study was to develop a novel liposomal formulation, containing phosphatidylserine (PS), of buparvaquone (BPQ) and to evaluate its in vivo effectiveness in Leishmania (L.) infantum chagasi-infected hamsters. The activity of BPQ was evaluated against both the
G R Muraguri et al.
Research in veterinary science, 81(1), 119-126 (2005-11-18)
East Coast fever, caused by the protozoan parasite Theileria parva, kills about 600,000 cattle annually in Africa. The hydroxynaphthoquinone compound buparvaquone (BPQ) is curative. Sixteen calves were infected with T. parva. On manifestation of disease symptoms, eight were injected with
Gantala Venkatesh et al.
Drug development and industrial pharmacy, 36(6), 735-745 (2010-02-09)
The aim of this study was to prepare a lipid-based self-microemulsifying drug delivery system (SMEDDS) to increase the solubility and oral bioavailability of a poorly water-soluble compound, buparvaquone (BPQ). The solubility of BPQ was determined in various vehicles, and pseudo-ternary
Tracy Garnier et al.
The Journal of pharmacy and pharmacology, 59(1), 41-49 (2007-01-18)
As the part of a study to develop buparvaquone (BPQ) formulations for the treatment of cutaneous leishmaniasis, the topical delivery of BPQ and one of its prodrugs from a range of formulations was evaluated. In previous studies, BPQ and its
Bariş Saruhan et al.
Turkiye parazitolojii dergisi, 32(4), 317-321 (2009-01-22)
The aim of this study was to examine the efficacy of buparvaquone (Buparvon, ALKE, Istanbul) in the treatment of theileriosis in cattle. The causative agent T. annulata causes direct and indirect gross economical loss in Turkey. Theileriosis was microscopically diagnosed
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