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32159

Isepamicin sulfate

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C22H43N5O12 · xH2SO4
CAS Number:
67814-76-0
Molecular Weight:
569.60 (free base basis)
PubChem Substance ID:
329754078
UNSPSC Code:
41116107
MDL number:
MFCD01683537
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grade

analytical standard

Quality Level

100

product line

VETRANAL®

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

InChI

1S/C22H43N5O12.H2O4S/c1-22(35)6-36-20(15(33)18(22)26-2)39-17-8(27-19(34)9(28)4-23)3-7(25)16(14(17)32)38-21-13(31)12(30)11(29)10(5-24)37-21;1-5(2,3)4/h7-18,20-21,26,28-33,35H,3-6,23-25H2,1-2H3,(H,27,34);(H2,1,2,3,4)/t7-,8+,9-,10+,11+,12-,13+,14-,15+,16+,17-,18+,20+,21+,22-;/m0./s1

InChI key

DDXRHRXGIWOVDQ-MGAUJLSLSA-N

General description

Isepamicin sulphate is a drug, which belongs to the aminoglycoside class of antibiotics.

Application

Isepamicin sulphate may be used as a reference standard in the separation of isepamicin sulphate from structurally related compounds using high performance liquid chromatography (HPLC), coupled with evaporative light scattering detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Regulatory Information

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Determination of isepamicin sulfate and related compounds by high performance liquid chromatography using evaporative light scattering detection.
Vogel R, et al.
Journal of Pharmaceutical and Biomedical Analysis, 24(3), 405-412 (2001)
Synthesis of antibiotic-loaded interporous hydroxyapatite blocks by vacuum method and in vitro drug release testing.
Itokazu M, et al.
Biomaterials, 19(7-9), 817-819 (1998)
Jing Kong et al.
Frontiers in microbiology, 11, 1718-1718 (2020-08-28)
The emergence of infections caused by bacterial pathogens that are resistant to current antibiotic therapy is a critical healthcare challenge. Aminoglycosides are natural antibiotics with broad spectrum of activity; however, their clinical use is limited due to considerable nephrotoxicity. Moreover