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Merck
CN

32236

Firocoxib

VETRANAL®, analytical standard

Synonym(s):

3-Cyclopropylmethoxy-4-(4-methanesulfonylphenyl)-5,5-dimethyl-5H-furan-2-one

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About This Item

Empirical Formula (Hill Notation):
C17H20O5S
CAS Number:
Molecular Weight:
336.40
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8335837
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grade

analytical standard

Quality Level

product line

VETRANAL®

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

SMILES string

O=S(C1=CC=C(C2=C(OCC3CC3)C(OC2(C)C)=O)C=C1)(C)=O

InChI

1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3

InChI key

FULAPETWGIGNMT-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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A Autefage et al.
The Veterinary record, 168(23), 617-617 (2011-06-07)
Thirty-nine client-owned dogs with osteoarthritis were treated with 5 mg/kg firocoxib administered orally, once a day for 52 weeks. Veterinary examinations were performed on approximately days 0, 15, 90, 180, 270 and 360. Twenty-five dogs completed the study. The withdrawal
Laura T Letendre et al.
American journal of veterinary research, 69(11), 1399-1405 (2008-11-05)
To determine pharmacokinetic parameters and variables, firocoxib concentrations in urine and plasma, urine-to-plasma ratios, and the urine depletion profile of firocoxib and to evaluate whether the pharmacokinetic behavior of firocoxib was governed by linear processes after multiple doses of firocoxib
W Back et al.
Equine veterinary journal, 41(3), 309-312 (2009-05-28)
Lameness is a highly prevalent condition in horses and the principal cause of removal from athletic activity. In clinical studies to evaluate nonsteroidal anti-inflammatory drug therapies, force plates are commonly used to assess improvement of lameness objectively. To use a



Global Trade Item Number

SKUGTIN
32236-10MG04061826702888