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Merck
CN

32344

Cefpodoxime

VETRANAL®, analytical standard

Synonym(s):

(6R,7R)-7-{2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxyimino]acetamido}-3-(methoxymethyl)-3-cephem-4-carboxylate, Cefpodoxime free acid

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About This Item

Empirical Formula (Hill Notation):
C15H17N5O6S2
CAS Number:
Molecular Weight:
427.46
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6021381
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InChI key

WYUSVOMTXWRGEK-HBWVYFAYSA-N

InChI

1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1

SMILES string

O=C(/C(C1=CSC(N)=N1)=N\OC)N[C@H](C2=O)[C@]3([H])N2C(C(O)=O)=C(COC)CS3

grade

analytical standard

product line

VETRANAL®

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

−20°C

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Axel Kola et al.
Antimicrobial resistance and infection control, 4, 8-8 (2015-03-31)
Carbapenemase-producing Enterobacteriaceae (CPE) have become a major problem for healthcare systems worldwide. While the first reports from European hospitals described the introduction of CPE from endemic countries, there is now a growing number of reports describing outbreaks of CPE in
Yen-Hung Liu et al.
International journal of antimicrobial agents, 51(5), 768-774 (2018-02-27)
A high prevalence of gonococcal resistance to various antimicrobials and Neisseria gonorrhoeae isolates exhibiting resistance to extended-spectrum cephalosporins have been reported in the past few decades. A total of 226 N. gonorrhoeae isolates obtained from the National Taiwan University Hospital
Thomas Grönthal et al.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 23(27) (2018-07-12)
IntroductionCarbapenemase-producing Enterobacteriaceae (CPE) have rarely been reported in dogs, and never in animals in Finland. However, in April 2015, two meropenem-resistant Escherichia coli were identified from two dogs in one family. Both dogs suffered from chronic otitis externa. Methods: Epidemiological
Arne Søraas et al.
PloS one, 8(7), e69581-e69581 (2013-08-13)
Community-acquired urinary tract infection (CA-UTI) is the most common infection caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae, but the clinical epidemiology of these infections in low prevalence countries is largely unknown. A population based case-control study was conducted to assess risk
Sushmita D Lahiri et al.
The Journal of antimicrobial chemotherapy, 69(11), 2942-2946 (2014-07-06)
Extended-spectrum AmpC (ESAC) β-lactamase enzymes, which are either chromosomally encoded or plasmid encoded, have minor structural changes that broaden their substrate hydrolysis profile. The derepressed AmpC enzyme found once in Enterobacter cloacae CHE was shown to contain a six residue

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