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Merck
CN

32540

Sigma-Aldrich

3,3′-Diethylthiadicarbocyanine iodide

≥98.5% (HPCE)

Synonym(s):

3-Ethyl-2-[5-(3-ethyl-2(3H)-benzothiazolylidene)-1,3-pentadienyl]benzothiazolium iodide, DTDCI, DiSC2(5)

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About This Item

Empirical Formula (Hill Notation):
C23H23IN2S2
CAS Number:
Molecular Weight:
518.48
Beilstein:
3838938
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
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Assay

≥98.5% (HPCE)

mp

249 °C (dec.) (lit.)

fluorescence

λex 605 nm; λem 700 nm in phosphate buffer/SDS pH 7.0

suitability

suitable for fluorescence

SMILES string

[I-].CCN1/C(Sc2ccccc12)=C\C=C\C=C\c3sc4ccccc4[n+]3CC

InChI

1S/C23H23N2S2.HI/c1-3-24-18-12-8-10-14-20(18)26-22(24)16-6-5-7-17-23-25(4-2)19-13-9-11-15-21(19)27-23;/h5-17H,3-4H2,1-2H3;1H/q+1;/p-1

InChI key

MNQDKWZEUULFPX-UHFFFAOYSA-M

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Other Notes

Potential sensitive probe. Fluorometric analysis of transferable membrane pores; Effects of membrane potential on Na cotransports in eel intestinal brush-border membrane vesicles

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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G. Cassano et al.
The Journal of Membrane Biology, 101, 225-225 (1988)
L M Loew et al.
Biochemistry, 24(9), 2101-2104 (1985-04-23)
When pore-forming factors insert into the hyperpolarized membranes of lipid vesicles, ion gradients are rapidly equilibrated, effecting complete depolarization. This process can be conveniently followed with a potentiometric cyanine dye. The generality of the method is demonstrated by applications to

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