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Merck
CN

32939

Zearalenone

reference material

Synonym(s):

F-2 toxin

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About This Item

Empirical Formula (Hill Notation):
C18H22O5
CAS Number:
Molecular Weight:
318.36
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1350216
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grade

analytical standard, reference material

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

C[C@H]1CCCC(=O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1

InChI key

MBMQEIFVQACCCH-QBODLPLBSA-N

General description

Zearalenone is one of the estrogenic metabolites produced by Fusarium species. It is usually found to co-occur with trichothecenes.

Application

Zearalenone has been used as an analytical reference standard for the determination of the analyte in:
  • Beer samples by liquid chromatography-mass spectrometry (LC-MS).

It may be used as an analytical reference standard for the determination of the analyte in:
  • Cereals by gas chromatography-mass spectrometry (GC-MS).
  • Maize samples by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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pictograms

Health hazardCorrosion

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

高风险级别生物产品--毒素类产品

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S De Baere et al.
Analytica chimica acta, 756, 37-48 (2012-11-28)
A sensitive and specific method for the quantitative determination of zearalenone (ZEN) and its major metabolites (α-zearalenol (α-ZEL), β-zearalenol (β-ZEL), α-zearalanol (α-ZAL), β-zearalanol (β-ZAL) and zearalanone (ZAN)) in animal plasma using liquid chromatography combined with heated electrospray ionization (h-ESI) tandem
Abdellah Zinedine et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(1), 1-18 (2006-10-19)
Zearalenone (ZEA) is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. It is frequently implicated in reproductive disorders of farm animals and occasionally in hyperoestrogenic syndromes in humans. There is evidence that ZEA
T Kuiper-Goodman et al.
Regulatory toxicology and pharmacology : RTP, 7(3), 253-306 (1987-09-01)
Trans-zearalenone, a resorcylic acid lactone, also known as F-2 toxin, is a nonsteroidal estrogenic mycotoxin produced by numerous species of Fusarium. As a result zearalenone is found in a number of cereal crops and their derived food products. A closely



Global Trade Item Number

SKUGTIN
32939-5MG04061826718797