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Merck
CN

32939

Zearalenone

reference material

Synonym(s):

F-2 toxin

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About This Item

Empirical Formula (Hill Notation):
C18H22O5
CAS Number:
17924-92-4
Molecular Weight:
318.36
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329754399
MDL number:
MFCD00133085
Beilstein/REAXYS Number:
1350216

Key Documents

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Product Name

Zearalenone, reference material

InChI

1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1

SMILES string

C[C@H]1CCCC(=O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI key

MBMQEIFVQACCCH-QBODLPLBSA-N

grade

analytical standard
reference material

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Zearalenone has been used as an analytical reference standard for the determination of the analyte in:
  • Beer samples by liquid chromatography-mass spectrometry (LC-MS).

It may be used as an analytical reference standard for the determination of the analyte in:
  • Cereals by gas chromatography-mass spectrometry (GC-MS).
  • Maize samples by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).

General description

Zearalenone is one of the estrogenic metabolites produced by Fusarium species. It is usually found to co-occur with trichothecenes.

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

高风险级别生物产品--毒素类产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCG8546
BCCG5939
BCCG2746
BCCF8394
BCCF2043

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Direct determination of the estrogenic compounds 8-prenylnaringenin, zearalenone, ?- and ?-zearalenol in beer by liquid chromatography-mass spectrometry.
Maragou NC, et al.
Journal of Chromatography A, 1202(1), 47-57 (2008)
Cristina Juan et al.
Food chemistry, 134(4), 2389-2397 (2013-02-28)
Although analytical methods have been already reported for legislated mycotoxins as trichothecenes and zearalenone (ZON) separately, we describe the optimization of a simple and rapid multimycotoxin method for the determination of a total of 12 mycotoxins simultaneously, nine trichothecenes (NIV
Simultaneous determination of trichothecene mycotoxins and zearalenone in cereals by gas chromatography-mass spectrometry.
Tanaka T, et al.
Journal of Chromatography A, 882(1-2), 23-28 (2000)
Zearalenone and zeranol: potential residue problems in livestock.
S F Sundlof et al.
Veterinary and human toxicology, 28(3), 242-250 (1986-06-01)
Yuquan Xu et al.
Applied and environmental microbiology, 79(6), 2038-2047 (2013-01-22)
10,11-Dehydrocurvularin is a prevalent fungal phytotoxin with heat shock response and immune-modulatory activities. It features a dihydroxyphenylacetic acid lactone polyketide framework with structural similarities to resorcylic acid lactones like radicicol or zearalenone. A genomic locus was identified from the dehydrocurvularin
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