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About This Item
Linear Formula:
NH2(CH2)8NH2
CAS Number:
Molecular Weight:
144.26
EC Number:
206-764-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1735426
MDL number:
grade
purum
assay
≥98.0% (NT)
bp
225-226 °C (lit.)
mp
50-52 °C
solubility
water: soluble 1 g/10 mL, clear, almost colorless
SMILES string
NCCCCCCCCN
InChI
1S/C8H20N2/c9-7-5-3-1-2-4-6-8-10/h1-10H2
InChI key
PWGJDPKCLMLPJW-UHFFFAOYSA-N
General description
1,8-Diaminooctane is an aliphatic bifunctional amine.
Application
1,8-Diaminooctane was used in the preparation of oligo(octamethylene terephthalamide) via enzymatic polycondensation with dimethyl terephthalate. It was used for functionalization of short pristine multi-walled carbon nanotubes (MWNTs). It was also used in solvent-free functionalization of fullerene C60.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
Storage Class
8B - Non-combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
222.8 °F - DIN 51758
flash_point_c
106 °C - DIN 51758
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
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E Stavila et al.
Biomacromolecules, 14(5), 1600-1606 (2013-04-03)
Enzymatically catalyzed polycondensation of p-xylylenediamine and diethyl sebacate resulted in oligo(p-xylylene sebacamide) with high melting temperatures (223-230 °C) and the enzymatic polycondensation of dimethyl terephthalate and 1,8-diaminooctane leads to oligo(octamethylene terephthalamide) with two melting temperatures at 186 and 218 °C.
Fabrizio Manetti et al.
Journal of medicinal chemistry, 52(15), 4774-4785 (2009-07-14)
Previous studies on agmatine and its derivatives suggested that the presence of hydrophobic groups on the guanidine moiety was a crucial key for inhibitory activity of maize polyamine oxidase. Accordingly, new lipophilic agmatine and iminoctadine derivatives were synthesized and tested
Richard A Hart et al.
Virology, 304(1), 97-104 (2002-12-20)
Proper function of the Rev regulatory system is essential for the replication of lentiviruses, including feline immunodeficiency virus (FIV) and human immunodeficiency virus type 1 (HIV-1). Specifically, Rev affects the overall stability of viral mRNAs that encode necessary structural and
G Houen et al.
European journal of biochemistry, 241(1), 303-308 (1996-10-01)
A protein reacting with a monoclonal antibody against human placental diamine oxidase was purified from the specific granules of human neutrofil granulocytes using affinity chromatography on aminohexyl-divinylsulfonyl-agarose. The protein had an M(r) determined by SDS/PAGE, corresponding to diamine oxidase, but
C Binda et al.
Biochemistry, 40(9), 2766-2776 (2001-03-22)
Polyamine oxidase (PAO) carries out the FAD-dependent oxidation of the secondary amino groups of spermidine and spermine, a key reaction in the polyamine catabolism. The active site of PAO consists of a 30 A long U-shaped catalytic tunnel, whose innermost
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