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About This Item
Empirical Formula (Hill Notation):
C9H6O4
CAS Number:
Molecular Weight:
178.14
EC Number:
207-618-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1910963
MDL number:
InChI key
FEMOMIGRRWSMCU-UHFFFAOYSA-N
InChI
1S/C9H6O4/c10-7-5-3-1-2-4-6(5)8(11)9(7,12)13/h1-4,12-13H
SMILES string
OC1(O)C(=O)c2ccccc2C1=O
grade
puriss. p.a.
assay
≥99%
ign. residue
≤0.1% (as SO4)
pH
4.6-5.0 (20 °C, 1%)
mp
250 °C (dec.) (lit.)
storage temp.
2-8°C
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Application
Ninhydrin (triketohydrindene hydrate) may be used as reagent for the quantification of amino acids and peptides by photometric method and colorimetric method. It may be used to prepare the ninhydrin reagent, by mixing ninhydrin and hydrindantin (reduced form of ninhydrin) in dimethyl sulfoxide. This reagent is used in manual ninhydrin method for the quantitative determination of amino acids.
Used for the detection of free amino groups in amino acids, peptides and proteins.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Photometric ninhydrin method for use in the chromatography of amino acids.
S MOORE et al.
The Journal of biological chemistry, 176(1), 367-388 (1948-10-01)
The determination of amino-acids with ninhydrin.
Yemm EW, et al.
Analyst, 80(948), 209-214 (1955)
Chao Li et al.
Journal of biomaterials science. Polymer edition, 23(1-4), 405-424 (2011-02-12)
Biomaterials have been playing important roles in cartilage regeneration. Although many scaffolds have been reported to enhance cartilage regeneration, none of the scaffolds available are optimal regarding mechanical properties, integration with host cartilage and providing proper micro-environment for chondrocyte attachment
Mohd Akram et al.
Colloids and surfaces. B, Biointerfaces, 94, 220-225 (2012-03-01)
The interaction of nickel dipeptide complex [Ni(II)-Gly-Tyr](+) with ninhydrin has been investigated in the absence and presence of cationic cetyltrimethylammonium bromide (CTAB) and gemini (16-s-16, s=4, 5, 6) surfactants spectrophotometrically at 80°C and pH 5.0. The product formed was the
Darren B Hansen et al.
Chemical Society reviews, 34(5), 408-417 (2005-04-27)
Following its discovery by Siegfried Ruhemann in 1910, ninhydrin rapidly became a practical analytical tool. In 1954 it was found to be an important reagent to develop fingerprints on porous surfaces. Since its use in forensic chemistry, many efforts have
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