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Merck
CN

33717

Thiourea

puriss. p.a., reag. Ph. Eur., ≥99%

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
62-56-6
Molecular Weight:
76.12
EC Number:
200-543-5
UNSPSC Code:
12352100
PubChem Substance ID:
24860463
Beilstein/REAXYS Number:
605327
MDL number:
MFCD00008067

Key Documents

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assay

≥99%

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

SMILES string

NC(N)=S

agency

reag. Ph. Eur.

grade

puriss. p.a.

ign. residue

≤0.1% (as SO4)

loss

≤0.5% loss on drying

Gene Information

mouse ... Ephx2(13850)

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Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
SZB90330V
SZBB1110V
SZBB1940
SZBB1110
SZB90330

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Yoshiji Takemoto
Chemical & pharmaceutical bulletin, 58(5), 593-601 (2010-05-13)
We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an 1,2-amino alcohol in expectation of their synchronous activation of a nucleophile and an electrophile through both acid-base and hydrogen-bonding interactions. From these studies, it was revealed that
Ai-Fang Li et al.
Chemical Society reviews, 39(10), 3729-3745 (2010-08-26)
This critical review highlights recent advances in the structurally modified (thio)urea-based receptors for anion complexation and sensing. Modifications of the (thio)urea structure are aimed at a better anion binding in terms of higher binding constant, anion selectivity and feasibility. Major
Elaine M Boyle et al.
The Journal of organic chemistry, 78(17), 8312-8319 (2013-08-01)
Thiourea-functionalized Tröger's base receptors 1 and 2 have been synthesized and evaluated as novel for the recognition of anions. Receptor 2 gave rise to significant changes in the absorption spectrum upon titration with AcO(-) and H2PO4(-) and acted as a
Iris Keren et al.
Science (New York, N.Y.), 339(6124), 1213-1216 (2013-03-09)
Bactericidal antibiotics kill by modulating their respective targets. This traditional view has been challenged by studies that propose an alternative, unified mechanism of killing, whereby toxic reactive oxygen species (ROS) are produced in the presence of antibiotics. We found no
David Weisbrod et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(18), E1685-E1694 (2013-04-17)
Proper expression and function of the cardiac pacemaker is a critical feature of heart physiology. Two main mechanisms have been proposed: (i) the "voltage-clock," where the hyperpolarization-activated funny current If causes diastolic depolarization that triggers action potential cycling; and (ii)
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