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Merck
CN

33986

Tiopronin

VETRANAL®, analytical standard

Synonym(s):

N-(2-Mercaptopropionyl)glycine, Tiopronin

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About This Item

Linear Formula:
CH3CH(SH)CONHCH2COOH
CAS Number:
Molecular Weight:
163.19
EC Number:
217-778-4
UNSPSC Code:
41116107
PubChem Substance ID:
Beilstein/REAXYS Number:
1859822
MDL number:
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InChI

1S/C5H9NO3S/c1-3(10)5(9)6-2-4(7)8/h3,10H,2H2,1H3,(H,6,9)(H,7,8)

InChI key

YTGJWQPHMWSCST-UHFFFAOYSA-N

SMILES string

CC(S)C(=O)NCC(O)=O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Lei Cui et al.
Nanomedicine : nanotechnology, biology, and medicine, 9(2), 264-273 (2012-06-13)
The present study characterized the in vitro biological response of a comprehensive set of cancer cell lines to gold nanoparticles (2.7 nm) coated with tiopronin (AuNPs-TP). Our findings suggest that upon entering cells, the AuNPs-TP are sequestered in vacuoles such
[Acute mastitis in rheumatoid polyarthritis with Gougerot-Sjögren syndrome treated with tiopronin (Acadione)].
C Gregoir et al.
Revue du rhumatisme et des maladies osteo-articulaires, 58(3), 203-206 (1991-03-01)
Yong Huang et al.
Journal of pharmaceutical and biomedical analysis, 55(5), 889-894 (2011-04-05)
An integrated microfluidic device with online labeling and chemiluminescence (CL) detection was developed for the simultaneous quantification of thiol drugs. In this device, the online labeling, electrophoresis separation and CL detection were compactly integrated onto a glass/poly(dimethylsiloxane) (PDMS) hybrid microfluidic
Thomas Schuetz et al.
Colloids and surfaces. B, Biointerfaces, 101, 118-125 (2012-07-17)
Scanning electron microscopy, transmission electron microscopy, rheometry, and electrochemistry were used to provide insight into the microstructure of collagen type I gel (1%, w/v) modified with the tiopronin-protected (N-(2-mercaptopropionyl)glycine) gold nanoparticles (TPAu), a multivalent crosslinker. The cross-linking reaction, performed via
Christoph Becker-Pauly et al.
Molecular & cellular proteomics : MCP, 10(9), M111-M111 (2011-06-23)
Astacins are secreted and membrane-bound metalloproteases with clear associations to many important pathological and physiological processes. Yet with only a few substrates described their biological roles are enigmatic. Moreover, the lack of knowledge of astacin cleavage site specificities hampers assay

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