33990
1,4-Dibromobenzene
purum, ≥97.0% (GC)
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About This Item
Empirical Formula (Hill Notation):
C6H4Br2
CAS Number:
Molecular Weight:
235.90
EC Number:
203-390-2
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1904543
MDL number:
InChI key
SWJPEBQEEAHIGZ-UHFFFAOYSA-N
InChI
1S/C6H4Br2/c7-5-1-2-6(8)4-3-5/h1-4H
SMILES string
Brc1ccc(Br)cc1
grade
purum
assay
≥97.0% (GC)
bp
219 °C (lit.)
mp
83-87 °C (lit.), 85-89 °C
density
1.841 g/mL at 25 °C (lit.)
Gene Information
human ... CYP2A6(1548)
mouse ... Cyp2a5(13087)
Regulatory Information
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A Colacci et al.
Toxicology letters, 54(2-3), 121-127 (1990-12-01)
1,4-Dibromobenzene (1,4-DBB) was covalently bound to DNA from liver, kidney, lung and stomach of mice after intraperitoneal administration. The covalent binding index (CBI) value (23 in mouse liver) was typical of weak initiators. On the contrary, no interaction with DNA
M Paolini et al.
Mutation research, 413(3), 205-217 (1998-07-04)
Murine S9 liver fractions isolated from mice fed 7.5 g kg-1 2(3)-tert-Butyl-4-hydroxyanisole (BHA) for 3 weeks were tested to determine: (a) the profile of both phase-I and phase-II xenobiotic metabolizing enzymes; (b) their ability to induce in vitro covalent binding
Jadwiga A Szymańska et al.
International journal of occupational medicine and environmental health, 15(4), 375-383 (2003-03-01)
The distribution, excretion and metabolism of 1,4-dibromobenzene (1,4-DBB) and 1,2-dibromobenzene (1,2-DBB), following a single intraperitoneal administration to female Wistar rats, were investigated using radiotracer 3H and GC-MS technique. The maximum level of 3H after 1,4-DBB administration was detected in all
Y Chaisuksant et al.
Ecotoxicology and environmental safety, 39(2), 120-130 (1998-03-27)
The growth rate reduction of mosquito fish (Gambusia affinis) fry was investigated with a range of sublethal exposure levels of four halobenzenes for 42 days. These compounds were found to produce growth rate reduction in mosquito fish fry at concentrations
J A Szymańska et al.
Journal of applied toxicology : JAT, 16(1), 35-41 (1996-01-01)
Various doses of dibromobenzene isomers (1,2-dBB, 1,3-dBB, 1,4-dBB) were administered (i.p.) to BALB mice. The levels of reduced glutathione (GSH) and malondialdehyde (MDA) in the liver, and glutamate-pyruvate transaminase (GPT) (EC.2.6.1.2) gamma-glutamyltransferase (gamma-GT) (EC.2.3.2.2) and triglycerides (TG) in the serum
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