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Merck
CN

34077

Supelco

PCB No 18

analytical standard

Synonym(s):

2,2′,5-Trichlorobiphenyl, 2,2′,5-PCB

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About This Item

Empirical Formula (Hill Notation):
C12H7Cl3
CAS Number:
Molecular Weight:
257.54
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
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grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

neat

SMILES string

Clc1ccc(Cl)c(c1)-c2ccccc2Cl

InChI

1S/C12H7Cl3/c13-8-5-6-12(15)10(7-8)9-3-1-2-4-11(9)14/h1-7H

InChI key

DCMURXAZTZQAFB-UHFFFAOYSA-N

General description

PCB No 18 belongs to the class of polychlorinated biphenyls, which exist as persistent contaminants in environmental matrices and food products.

Application

PCB No 18 may be used as an analytical reference standard for the determination of the analyte in:
  • environmental samples using glass capillary gas-chromatography with electron capture detection
  • environmental matrix standard reference materials using supercritical fluid extraction/soxhlet extraction combined with gas chromatography coupled to two electron capture detection systems

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazardEnvironment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品
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Uterotropic and enzyme induction effects of 2,2',5-trichlorobiphenyl.
M H Li et al.
Bulletin of environmental contamination and toxicology, 54(4), 494-500 (1995-04-01)
S H Jo et al.
Journal of cardiovascular pharmacology, 38(1), 11-20 (2001-07-11)
Polychlorinated biphenyls (PCBs) have been known as serious environmental pollutants, causing developmental delays, motor dysfunction, and decrease in brain dopamine level in humans and animals. We have investigated the effects of a PCB congener, 2,2',6-trichlorobiphenyl (PCB 19) on contractile force
Distribution and metabolism of 2,5,2'-trichlorobiphenyl in houseflies (Musca domestica L.).
S A Saghir et al.
Bulletin of environmental contamination and toxicology, 49(6), 839-846 (1992-12-01)
S A Saghir et al.
Ecotoxicology and environmental safety, 28(2), 111-120 (1994-07-01)
Adult female houseflies (Musca domestica) were topically dosed with 10, 15, and 20 micrograms of 2,2',5-trichlorobiphenyl (PCB-18) in acetone at 1, 5, and 15 days following emergence. These doses caused a significant decrease in the mean survival time in 5-day-old
J D Haddock et al.
Journal of bacteriology, 177(1), 20-26 (1995-01-01)
Oxidation of biphenyl and nine chlorinated biphenyls (CBs) by the biphenyl 2,3-dioxygenase from Pseudomonas sp. strain LB400 was examined. The purified terminal oxygenase required the addition of partially purified electron transport components, NAD(P)H, and ferrous iron to oxidize biphenyl and

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