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Resveratrol

analytical standard

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Synonym(s):
3,4′,5-Trihydroxy-trans-stilbene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
Empirical Formula (Hill Notation):
C14H12O3
CAS Number:
Molecular Weight:
228.24
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

InChI key

LUKBXSAWLPMMSZ-OWOJBTEDSA-N

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General description

Resveratrol, a non-flavonoid polyphenolic compound, is widely found in the skin of red grapes, nuts, berries, Polygonum cuspidatum root, etc. It is reportedly known to exhibit pharmacological properties including anti-cancer, anti-inflammatory, antioxidant, neuroprotectant, anti-atherogenic property and reduces the synthesis of pro-atherosclerotic substances.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Resveratrol has been used as a phenolic analytical standard to determine its content in oat flour tarhana and different varieties of chicory using high-performance liquid chromatography with diode array detection (HPLC-DAD). It has also been used as an analytical standard to investigate its effectiveness in modulating several signaling pathways that are involved in carcinogenesis, via determining its anti-tumor potential in colorectal cancer as a proapoptotic agent in colorectal cancer cell lines, including HCT116, CO115 and SW48.
Selective inhibitor of COX−1.

Recommended products

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

392.0 °F - closed cup - (External MSDS)

Flash Point(C)

> 200.0 °C - closed cup - (External MSDS)

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

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Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

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Biological effects of resveratrol
Fremont L
Life Sciences, 66, 663-673 (2000)
Resveratrol induces p53 in colorectal cancer through SET7/9
Liu Z, et al.
Oncology Letters, 17(4), 3783-3789 (2019)
HPLC?tandem mass spectrometric method to characterize resveratrol metabolism in humans
Urpi-Sarda M, et al.
Clinical Chemistry, 53(2), 292-299 (2007)
The impact of drying techniques on phenolic compound, total phenolic content and antioxidant capacity of oat flour tarhana
Degirmencioglu N, et al.
Food Chemistry, 194, 587-594 (2016)
Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
Lu R and Serrero G
Journal of Cellular Physiology, 179, 297-304 (1999)

Articles

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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