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Merck
CN

34131

Nivalenol solution

100 μg/mL in acetonitrile, analytical standard

Synonym(s):

3α,4β,7α, 15-Tetrahydroxy-12,13-epoxytrichothec-9-en-8-one, NIV

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About This Item

Empirical Formula (Hill Notation):
C15H20O7
CAS Number:
23282-20-4
Molecular Weight:
312.32
NACRES:
NA.24
PubChem Substance ID:
329754837
UNSPSC Code:
85151701
EC Number:
200-835-2
MDL number:
MFCD00133673

Key Documents

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Product Name

Nivalenol solution, 100 μg/mL in acetonitrile, analytical standard

InChI key

UKOTXHQERFPCBU-XBXCNEFVSA-N

InChI

1S/C15H20O7/c1-6-3-7-14(4-16,11(20)8(6)17)13(2)10(19)9(18)12(22-7)15(13)5-21-15/h3,7,9-12,16,18-20H,4-5H2,1-2H3/t7-,9-,10-,11-,12-,13-,14-,15+/m1/s1

SMILES string

[H][C@]12O[C@]3([H])[C@H](O)[C@@H](O)[C@@](C)([C@]34CO4)[C@@]1(CO)[C@H](O)C(=O)C(C)=C2

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

Quality Level

100

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Related Categories

Application

Nivalenol was used as standard to investigate in vitro mycotoxin binding of deoxynivalenol and nivalenol by adsorbent materials (activated carbon).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Certan Vial
Nivalenol is a potential trichothecene mycotoxin, produced by Fusarium nivale., Genotoxicity of nivalenol is evaluated by alkaline single-cell gel electrophoresis assay.
Nivalenol is a secondary metabolite produced by Fusarium species, which is a plant pathogenic fungus of wheat and other cereals.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
高风险级别生物产品--毒素类产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6725
BCCM7688
BCCL6495
BCCL3592
BCCJ3937

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Alaleh Zoghi et al.
Mini reviews in medicinal chemistry, 14(1), 84-98 (2013-12-18)
Removal of toxic metals and toxins using microbial biomass has been introduced as an inexpensive, new promising method on top of conventional methods for decontamination of food, raw material and concentrated. In this article the potential application of lactic acid
Determination of nivalenol and deoxynivalenol by liquid chromatography/atmospheric pressure photoionization mass spectrometry
Tanaka H, et al.
Rapid Communications in Mass Spectrometry, 23(19), 3119- 3124 (2009)
S Tsuda et al.
Mutation research, 415(3), 191-200 (1998-08-26)
We tested the genotoxicity of nivalenol (NIV), a potent toxic trichothecene from Fusarium nivale, in cultured CHO cells and in several mouse organs and tissues (liver, kidney, thymus, bone marrow and mucosa of stomach, jejunum, and colon) using the alkaline
G Barros et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(2), 293-303 (2011-05-21)
Soybean (Glycine max L.), the main source of protein throughout the world, is used both as a food and a feedstuff. Currently, limited information about the occurrence of Fusarium species and mycotoxins in soybean grain and by-products is available. The
E D Van Asselt et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(10), 1556-1565 (2012-06-30)
Mycotoxins are secondary metabolites produced by fungi that can cause adverse health effects. Due to climate change, temperatures are expected to rise and changes in rainfall patterns are foreseen. These developments may increase fungal occurrence and mycotoxin concentrations in maize.
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