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Merck
CN

34135

Deepoxy-deoxynivalenol solution

~50 μg/mL in acetonitrile, analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-trichothec-9,12-dien-8-one solution, DOM-1

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About This Item

Empirical Formula (Hill Notation):
C15H20O5
CAS Number:
88054-24-4
Molecular Weight:
280.32
NACRES:
NA.24
PubChem Substance ID:
329754841
UNSPSC Code:
85151701
EC Number:
200-835-2
MDL number:
MFCD07364056

Key Documents

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Product Name

Deepoxy-deoxynivalenol solution, ~50 μg/mL in acetonitrile, analytical standard

InChI key

ZACLXWTWERGCLX-MDUHGFIHSA-N

InChI

1S/C15H20O5/c1-7-4-10-15(6-16,13(19)11(7)18)14(3)5-9(17)12(20-10)8(14)2/h4,9-10,12-13,16-17,19H,2,5-6H2,1,3H3/t9-,10-,12+,13-,14+,15-/m1/s1

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)(C3=C)[C@@]2(CO)[C@H](O)C1=O

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

~50 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

Quality Level

100

Related Categories

Analysis Note

purity : ≥92.5% (HPLC)

Application

Deepoxy-deoxynivalenol solution may be used as internal standard in the determination of trichothecene mycotoxins present in baby foods, using high performance liquid chromatography coupled with mass spectrometry (HPLC/MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Certan Vial
Deepoxy-deoxynivalenol is found to be a metabolite of the trichothecene mycotoxin deoxynivalenol, which can be generally found in swine.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F

flash_point_c

2 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

高风险级别生物产品--毒素类产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7288
BCCM7617
BCCM1274
BCCL1127
BCCK2480

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N De Zutter et al.
Scientific reports, 6, 38640-38640 (2016-12-09)
Biotransformation of mycotoxins in animals comprises phase I and phase II metabolisation reactions. For the trichothecene deoxynivalenol (DON), several phase II biotransformation reactions have been described resulting in DON-glutathiones, DON-glucuronides and DON-sulfates made by glutathione-S-transferases, uridine-diphosphoglucuronyl transferases and sulfotransferases, respectively.
Barbara Novak et al.
Toxins, 10(4) (2018-04-12)
Deoxynivalenol (DON) is one of the most prevalent mycotoxins, contaminating cereals and cereal-derived products. Its derivative deepoxy-deoxynivalenol (DOM-1) is produced by certain bacteria, which either occur naturally or are supplemented in feed additive. DON-induced impairments in protein synthesis are particularly
Amin Sayyari et al.
Toxins, 10(12) (2018-12-07)
Deoxynivalenol (DON) contamination of feed may result in reduced growth, feed refusal, immunosuppression, and health problems in swine. Piglets can be exposed to DON via placenta before birth and via milk during lactation. The extent of early-life exposure of piglets
Marianne Lauwers et al.
Toxins, 11(3) (2019-03-22)
A reliable and practical multi-method was developed for the quantification of mycotoxins in plasma, urine, and feces of pigs, and plasma and excreta of broiler chickens using liquid chromatography⁻tandem mass spectrometry. The targeted mycotoxins belong to the regulated groups, i.e.
Application of an HPLC?MS/MS method for mycotoxin analysis in commercial baby foods
Rubert J, et al.
Food Chemistry, 133, 176-183 (2012)
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