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Merck
CN

34135

Deepoxy-deoxynivalenol solution

~50 μg/mL in acetonitrile, analytical standard

Synonym(s):

3α,7α,15-Trihydroxy-trichothec-9,12-dien-8-one solution, DOM-1

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About This Item

Empirical Formula (Hill Notation):
C15H20O5
CAS Number:
88054-24-4
Molecular Weight:
280.32
EC Number:
200-835-2
MDL number:
MFCD07364056
UNSPSC Code:
85151701
PubChem Substance ID:
329754841
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

concentration

~50 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)(C3=C)[C@@]2(CO)[C@H](O)C1=O

InChI

1S/C15H20O5/c1-7-4-10-15(6-16,13(19)11(7)18)14(3)5-9(17)12(20-10)8(14)2/h4,9-10,12-13,16-17,19H,2,5-6H2,1,3H3/t9-,10-,12+,13-,14+,15-/m1/s1

InChI key

ZACLXWTWERGCLX-MDUHGFIHSA-N

General description

Certan Vial
Deepoxy-deoxynivalenol is found to be a metabolite of the trichothecene mycotoxin deoxynivalenol, which can be generally found in swine.

Application

Deepoxy-deoxynivalenol solution may be used as internal standard in the determination of trichothecene mycotoxins present in baby foods, using high performance liquid chromatography coupled with mass spectrometry (HPLC/MS-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Analysis Note

purity : ≥92.5% (HPLC)

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F

Flash Point(C)

2 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

高风险级别生物产品--毒素类产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7288
BCCM7617
BCCM1274
BCCL1127
BCCK2480

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Xiaojuan Gao et al.
Toxins, 12(2) (2020-01-30)
Deoxynivalenol (DON) is a highly abundant mycotoxin that exerts many adverse effects on humans and animals. Much effort has been made to control DON in the past, and bio-transformation has emerged as the most promising method. However, useful and effective
Bonnie Valgaeren et al.
Archives of toxicology, 93(2), 293-310 (2018-12-12)
A clinical case in Belgium demonstrated that feeding a feed concentrate containing considerable levels of deoxynivalenol (DON, 1.13 mg/kg feed) induced severe liver failure in 2- to 3-month-old beef calves. Symptoms disappeared by replacing the highly contaminated corn and by stimulating
Nathan Broekaert et al.
Archives of toxicology, 91(2), 699-712 (2016-04-22)
Crossover animal trials were performed with intravenous and oral administration of deoxynivalenol-3-β-D-glucoside (DON3G) and deoxynivalenol (DON) to broiler chickens and pigs. Systemic plasma concentrations of DON, DON3G and de-epoxy-DON were quantified using liquid chromatography-tandem mass spectrometry. Liquid chromatography coupled to
Marianne Lauwers et al.
Toxins, 11(3) (2019-03-22)
A reliable and practical multi-method was developed for the quantification of mycotoxins in plasma, urine, and feces of pigs, and plasma and excreta of broiler chickens using liquid chromatography⁻tandem mass spectrometry. The targeted mycotoxins belong to the regulated groups, i.e.
Amin Sayyari et al.
Toxins, 10(12) (2018-12-07)
Deoxynivalenol (DON) contamination of feed may result in reduced growth, feed refusal, immunosuppression, and health problems in swine. Piglets can be exposed to DON via placenta before birth and via milk during lactation. The extent of early-life exposure of piglets
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