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Merck
CN

34231

Naftalofos

PESTANAL®, analytical standard

Synonym(s):

O,O-Diethyl N-hydroxynaphthalimide phosphate, Naphthalophos

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About This Item

Empirical Formula (Hill Notation):
C16H16NO6P
CAS Number:
1491-41-4
Molecular Weight:
349.28
NACRES:
NA.24
PubChem Substance ID:
329754916
UNSPSC Code:
41116107
EC Number:
216-078-6
MDL number:
MFCD00864515

Key Documents

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InChI key

QNSIFYWAPWSAIJ-UHFFFAOYSA-N

InChI

1S/C16H16NO6P/c1-3-21-24(20,22-4-2)23-17-15(18)12-9-5-7-11-8-6-10-13(14(11)12)16(17)19/h5-10H,3-4H2,1-2H3

SMILES string

CCOP(=O)(OCC)ON1C(=O)c2cccc3cccc(C1=O)c23

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

2-8°C

Quality Level

100

General description

Naftalofos is an organophosphorus pesticide primarily used to control pests in various agricultural applications. Its mode of action involves inhibition of the acetylcholinesterase (AChE) enzyme.

Application

Naftalofos may be used as an analytical reference standard for the determination of the target analyte in food and environmental samples by square wave voltammetric detection method using novel modified reduced graphene oxide (RGO)/chitosan (CS) on a glassy carbon electrode.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H310

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF8415
BCBT4895

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Square Wave Voltammetric Detection of Dimethylvinphos and Naftalofos in Food and Environmental Samples Using RGO/CS modified Glassy Carbon Electrode.
ReddyPrasad P, et al.
International Journal of Electrochemical Science, 11(1), 65-79 (2016)
Electrochemical sensor for the detection of pesticides in environmental sample: A review.
Joshi P, et al.
International Journal of Chemical Studies, 6(2), 3199-3205 (2018)
A C Kotze et al.
International journal for parasitology, 29(7), 1093-1099 (1999-09-29)
Responses of several nematode species to naphthalophos and pyrantel/levamisole were examined using a larval development assay in order to determine the potential of this assay for detection of resistance. Haemonchus contortus and Ostertagia circumcincta showed concentration-dependent responses to naphthalophos, however
N A Cooper et al.
Australian veterinary journal, 74(3), 221-224 (1996-09-01)
To investigate the relative efficacy and safety of the anthelmintic naphthalophos in sheep, either given alone or in combination with benzimidazole (fenbendazole and albendazole) or levamisole anthelmintics. A parasitological study using faecal egg count reduction tests, a validating slaughter trial
K M Dash
Australian veterinary journal, 63(2), 45-47 (1986-02-01)
Following the failure of anthelmintic treatment to control an outbreak of trichostrongylosis in sheep, multiple resistance to levamisole and oxfendazole was confirmed in field strains of Trichostrongylus colubriformis at the CSIRO Pastoral Research Laboratory, Armidale. Resistance in Trichostrongylus spp to
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