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Merck
CN

35405

α-Zearalanol solution

~10 μg/mL in acetonitrile, analytical standard

Synonym(s):

(3S,7R)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one solution, 2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)benzoic acid μ-lactone solution

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About This Item

Empirical Formula (Hill Notation):
C18H26O5
CAS Number:
26538-44-3
Molecular Weight:
322.40
UNSPSC Code:
85151701
PubChem Substance ID:
329755162
EC Number:
200-835-2
MDL number:
MFCD00864182

Key Documents

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InChI key

DWTTZBARDOXEAM-GXTWGEPZSA-N

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1

SMILES string

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

availability

not available in Canada

concentration

~10 μg/mL in acetonitrile

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

General description

α-Zearalanol is a resorcyclic acid lactone. It is a plant derived, nonsteroidal phytoestrogen, often used as a dietary supplement.

Application

α-Zearalanol may be used as an analytical reference standard for the determination of the analyte in traditional Chinese medicines, human and animal urine by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Analysis Note

purity : ≥97.0% (HPLC)

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2.0 °C - closed cup

Regulatory Information

危险化学品
高风险级别生物产品--毒素类产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCK8403
BCCH2931
BCCF0197
BCCB8524
BCCB1173

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A rapid method for simultaneous determination of zearalenone, α-zearalenol, β-zearalenol, zearalanone, α-zearalanol and β-zearalanol in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry.
Han Z, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879(5-6), 411-420 (2011)
Nidia V Valenzuela-Grijalva et al.
Journal of the science of food and agriculture, 92(7), 1362-1367 (2011-12-07)
The effect of zeranol implantation strategy on intramuscular fat, fatty acid profile and cholesterol content of the longissimus dorsi muscle of hair lambs was studied. Four treatments were tested: C, control group; Z12, 12 mg zeranol; Z24, 24 mg zeranol
Rui Feng et al.
Biosensors & bioelectronics, 42, 367-372 (2012-12-06)
Nanoporous PtCo alloy was designed as an antibody carrier for preparation of a highly sensitive immunosensor. The immunosensor was constructed by assembling the capture zeranol antibody on thionine decorated graphene nanosheets modified glassy carbon electrode. With an enzyme-free immunosensor mode
Yuan Gao et al.
The Analyst, 137(1), 229-236 (2011-11-04)
Although anti-zearalenone (ZEN) antibodies have been widely prepared, these antibodies cross-react with α-zearalenol (α-ZOL), β-zearalenol (β-ZOL), zearalanone (ZAN), α-zearalanol (α-ZAL) and β-zearalanol (β-ZAL). To overcome this problem and improve the specificity of immunoassays, we produced anti-ZEN antibodies based on a
Hongfeng Wang et al.
The Journal of reproduction and development, 58(3), 338-343 (2012-03-27)
Alpha-Zearalenol (α-ZEA) is one of derivatives from Zearalenone (ZEA) which impacts mammalian reproduction and development. Previous studies have shown that pigs are sensitive to the estradiol-like effects of α-ZEA. However, the effect of α-ZEA for the early embryonic development has
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