Skip to Content
Merck
CN

35762

Alternariol-9-methyl ether

analytical standard

Synonym(s):

3,7-Dihydroxy-9-methoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one, Alternariol monomethyl ether

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C15H12O5
CAS Number:
23452-05-3
Molecular Weight:
272.25
NACRES:
NA.24
PubChem Substance ID:
329755214
UNSPSC Code:
85151701
MDL number:
MFCD00058532

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

LCSDQFNUYFTXMT-UHFFFAOYSA-N

SMILES string

COc1cc(O)c2C(=O)Oc3cc(O)cc(C)c3-c2c1

InChI

1S/C15H12O5/c1-7-3-8(16)4-12-13(7)10-5-9(19-2)6-11(17)14(10)15(18)20-12/h3-6,16-17H,1-2H3

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

Quality Level

100

General description

Alternariol-9-methyl ether (AME) is a mycotoxin produced by fungus Alternaria and a major plant pathogen found in a wide variety of fruits and cereals products.

Application

Alternariol-9-methyl ether (AME) may be used as an analytical reference standard for the determination of the analyte in food products by liquid chromatography tandem mass spectrometry (LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Analysis Note

purity : ≥96.0% (HPLC)

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

高风险级别生物产品--毒素类产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCH6488
BCCG6154
BCCD4940
BCCD1984
BCBZ8281

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

U Tiemann et al.
Toxicology letters, 186(2), 139-145 (2009-05-12)
Mycotoxins as contaminants of animal food can impair fertility in farm animals. In the regulation of female fertility the ovarian steroid hormone progesterone (P(4)) plays an important role. In the present study we have investigated the influence of the mycotoxins
Claudia R Pozzi et al.
Journal of agricultural and food chemistry, 53(14), 5824-5828 (2005-07-07)
The present study aimed to analyze the mycoflora and the occurrence of alternariol (AOH) and alternariol monomethyl ether (AME) in grain samples of sunflower during different stages of plant development in Nova Odessa, State of São Paulo, Brazil. The data
Total synthesis of masked Alternaria mycotoxins?sulfates and glucosides of alternariol (AOH) and alternariol-9-methyl ether (AME).
Mikula H, et al.
Tetrahedron, 69(48), 10322-10330 (2013)
Markus Fehr et al.
Molecular nutrition & food research, 53(4), 441-451 (2008-08-30)
Alternariol (AOH), a mycotoxin formed by Alternaria alternata, has been reported to possess genotoxic properties. However, the underlying mechanism of action is unclear. Here, we tested the hypothesis that interactions with DNA-topoisomerases play a role in the DNA-damaging properties of
Erika Pfeiffer et al.
Molecular nutrition & food research, 51(3), 307-316 (2007-03-07)
The Alternaria toxins alternariol (AOH; 3,7,9-trihydroxy-1-methyl-6H-benzo[c]chromen-6-one) and alternariol methyl ether (AME, 3,7-dihydroxy-9-methoxy-1-methyl-6H-benzo[c]chromen-6-one) are common contaminants of food and feed, but their oxidative metabolism in mammals is as yet unknown. We have therefore incubated AME and AOH with microsomes from rat
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service