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Merck
CN

36194

Phosalone

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C12H15ClNO4PS2
CAS Number:
Molecular Weight:
367.81
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
218-996-2
Beilstein/REAXYS Number:
694650
MDL number:
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Product Name

Phosalone, PESTANAL®, analytical standard

InChI key

IOUNQDKNJZEDEP-UHFFFAOYSA-N

InChI

1S/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3

SMILES string

CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

Quality Level

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Phosalone is a commonly used, organophosphate insecticide, which can find applications in agricultural production. It can act effectively on lipid peroxidation and other antioxidant enzymes like superoxide dismutase, catalase and also glutathione peroxidase.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

212.0 °F - closed cup

flash_point_c

100 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

农药列管产品
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Synergism of resistance to phosalone and comparison of kinetic properties of acetylcholinesterase from four field populations and a susceptible strain of Colorado potato beetle
Mohamadi M.M, et al.
Pesticide Biochemistry and Physiology, 98, 254-262 (2010)
Role of reactive oxygen species in organophosphate insecticide phosalone toxicity in erythrocytes in vitro
Altuntas.I, et al.
Toxicology in vitro, 17, 153-157 (2003)
K Balasandaram et al.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 118(2), 229-231 (1998-01-24)
An acute dose of phosalone, intraperitoneally injected to Rana tigrina alters the bioelectrical activity of the brain. The frequency levels of delta, theta, alpha, and beta waves remained similar in both control and experimental groups, while the amplitude of the
Ali Asghr Pourmirza
Journal of economic entomology, 98(6), 2176-2180 (2006-03-17)
The susceptibility status of Colorado potato beetle, Leptinotarsa decemlineata (Say), adults to phosalone was determined by dip and glass jar assay techniques. Bioassay results indicated a narrow variation in Colorado potato beetle insecticide susceptibility among sample sites. LC50 values were
V Issert et al.
Amino acids, 17(4), 377-389 (2000-03-09)
Hapten synthesis for the production of specific insecticide phosalone polyclonal antibodies was carried out starting from an intermediate of the phosalone synthesis, 6-chloro-2-benzoxazolone 1. Two haptens containing different spacers have been prepared: N-5-carboxypentyl-6-chloro-2-benzoxazolone 7 and N-(2-oxo-3-aza-5-carboxypentyl)-6-chloro-2-benzoxazolone 12. Each of these

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