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Merck
CN

36984

EPN

100 μg/mL in acetonitrile, PESTANAL®, analytical standard

Synonym(s):

O-Ethyl O-(4-nitrophenyl) phenylphosphonothioate solution

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About This Item

CAS Number:
2104-64-5
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329755563
EC Number:
200-835-2
Beilstein/REAXYS Number:
2542580
MDL number:
MFCD00055309

Key Documents

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InChI key

AIGRXSNSLVJMEA-UHFFFAOYSA-N

InChI

1S/C14H14NO4PS/c1-2-18-20(21,14-6-4-3-5-7-14)19-13-10-8-12(9-11-13)15(16)17/h3-11H,2H2,1H3

SMILES string

CCOP(=S)(Oc1ccc(cc1)[N+]([O-])=O)c2ccccc2

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture

format

single component solution

storage temp.

2-8°C

General description

EPN belongs to the class of organophosphorus insecticides extensively used in agriculture for the control of a wide range of insect pests. Its mode of action involves the inhibition of acetylcholinesterase activity in insects.

Application

EPN may be used as an analytical reference standard for the quantification of the analyte in tea and environmental samples using various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F

flash_point_c

2 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBW6021

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Analysis of organophosphorus insecticides from environmental samples using solid-phase microextraction
Magdic S, et al.
Journal of Chromatography A, 736(1-2), 219-228 (1996)
Development of enzyme-linked immunosorbent assays for the organophosphorus insecticide EPN
Shim YJ, et al.
Journal of Agricultural and Food Chemistry, 56(24), 11551-11559 (2008)
Simultaneous multi-determination and transfer of eight pesticide residues from green tea leaves to infusion using gas chromatography
Cho K-S, et al.
Food Chemistry, 165, 532-539 (2014)
M B Abou-Donia et al.
The Journal of pharmacology and experimental therapeutics, 257(1), 282-289 (1991-04-01)
The joint neurotoxic action of simultaneous exposure to vapors of n-hexane and methyl iso-butyl ketone (MiBK) and dermally applied O-ethyl O-nitrophenyl phenylphosphonothioate (EPN) was studied in groups of five adult hens. Four groups of hens were concurrently exposed to a
S Sugiyama et al.
Japanese journal of pharmacology, 37(3), 245-252 (1985-03-01)
O-Ethyl O-p-nitrophenyl phenylphosphonothioate (EPN)-induced inhibition of rat liver microsomal carboxylesterase (CEase) and formation of O-ethyl O-p-nitrophenyl phenylphosphonate (EPNoxon), an oxygen analog of EPN, were enhanced remarkably by addition of NAD in vitro. This potentiation of the anti-CEase action of EPN
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