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Merck
CN

37012

Beauvericin

VETRANAL®, analytical standard

Synonym(s):

cyclo(D-α-Hydroxyisovaleryl-L-N-methyl-Phe)3

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About This Item

Empirical Formula (Hill Notation):
C45H57N3O9
CAS Number:
26048-05-5
Molecular Weight:
783.95
NACRES:
NA.24
PubChem Substance ID:
329755577
UNSPSC Code:
41116107
MDL number:
MFCD00056846

Key Documents

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InChI key

GYSCAQFHASJXRS-UHFFFAOYSA-N

SMILES string

CC(C)C1OC(=O)C(Cc2ccccc2)N(C)C(=O)C(OC(=O)C(Cc3ccccc3)N(C)C(=O)C(OC(=O)C(Cc4ccccc4)N(C)C1=O)C(C)C)C(C)C

InChI

1S/C45H57N3O9/c1-28(2)37-40(49)46(7)35(26-32-21-15-11-16-22-32)44(53)56-39(30(5)6)42(51)48(9)36(27-33-23-17-12-18-24-33)45(54)57-38(29(3)4)41(50)47(8)34(43(52)55-37)25-31-19-13-10-14-20-31/h10-24,28-30,34-39H,25-27H2,1-9H3

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

Quality Level

100

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General description

Beauvericin is a mycotoxin mainly produced by several fungi belonging to Fusarium genus, generally occurring in agricultural commodities.

Application

Beauvericin may be used as analytical reference standard for the quantification of the analyte in cultures of Fusarium subglutinans, naturally contaminated maize, and biological samples using various chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Preparation Note

Dried down, ~100μg/mL after reconstitution with 1 mL of water

Analysis Note

purity : ≥92.5% (HPLC)

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCH0208
BCCF0195
BCCB8560
BCBZ7044
BCBR4884V

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Simultaneous determination of beauvericin, enniatins, and fusaproliferin by high performance liquid chromatography
Monti.MS, et al.
Journal of Agricultural and Food Chemistry, 48(8), 3317-3320 (2000)
Quantitative determination of the Fusarium mycotoxins beauvericin, enniatin A, A1, B and B1 in pig plasma using high performance liquid chromatography--tandem mass spectrometry
Devreese M, et al.
Talanta, 106(2), 212-219 (2013)
Determination of the Fusarium mycotoxins, fusaproliferin and beauvericin by high-performance liquid chromatography-electrospray ionization mass spectrometry
Sewram V, et al.
Journal of Chromatography A, 858(2), 175-185 (1999)
Sofie Monbaliu et al.
Journal of agricultural and food chemistry, 58(19), 10475-10479 (2010-09-10)
In this work the presence and migration behavior of mycotoxins formed in sweet pepper, inoculated by Fusarium species involved in internal fruit rot, were investigated. Two different commercial sweet pepper cultivars were inoculated with two different Fusarium proliferatum isolates that
A S Ficheux et al.
Toxicon : official journal of the International Society on Toxinology, 71, 1-10 (2013-05-21)
The aim of this study was to assess the in vitro effects of emerging mycotoxins beauvericin, enniatin B and moniliformin on human dendritic cells and macrophages. Beauvericin and enniatin B were cytotoxic on these cells. IC50 were equal to 1.0 μM, 2.9 μM
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