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Merck
CN

37298

2,3-Dihydrofuran

purum, ≥99.0% (GC)

Synonym(s):

2,3-DHF

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About This Item

Empirical Formula (Hill Notation):
C4H6O
CAS Number:
Molecular Weight:
70.09
EC Number:
214-747-7
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
103168
MDL number:
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vapor pressure

14.46 psi ( 55 °C), 3.67 psi ( 20 °C)

grade

purum

assay

≥99.0% (GC)

contains

~0.5% potassium carbonate as stabilizer

refractive index

n20/D 1.423

bp

54-55 °C (lit.)

density

0.927 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

C1CC=CO1

InChI

1S/C4H6O/c1-2-4-5-3-1/h1,3H,2,4H2

InChI key

JKTCBAGSMQIFNL-UHFFFAOYSA-N

Other Notes

α-Lithiation/alkylation en route to γ-keto acids


pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

-11.2 °F - closed cup

flash_point_c

-24 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves

Regulatory Information

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M.A. Tschantz et al.
Organic Syntheses, 73, 215-215 (1996)
Qi-Fang Wang et al.
The Journal of organic chemistry, 74(19), 7403-7406 (2009-09-11)
An efficient synthetic procedure for the preparation of fused 2,3-dihydrofuran derivatives was developed with the assistance of pyridinium ylide. A sequential one-pot, two-step tandem reaction starting from pyridine, aromatic aldehyde, dimedone, or 4-hydroxycoumarin and alpha-phenacyl bromide or p-nitrobenzyl bromide with
Lun-Zhi Dai et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 14(23), 7011-7018 (2008-07-08)
The gold(I)-catalyzed cycloisomerization of epoxy alkynes in the presence of a nucleophile is an efficient protocol to provide ketal skeletons with high stereoselectivity. An intramolecular reaction of propargylic/homopropargylic alcohols with oxirane to produce ketal/spiroketals in moderate yields under mild conditions