37940
2,3-Dihydroxypyridine
technical, ≥95% (HPLC)
Synonym(s):
2,3-Pyridinediol
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About This Item
Empirical Formula (Hill Notation):
C5H5NO2
CAS Number:
Molecular Weight:
111.10
EC Number:
240-887-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
109848
MDL number:
grade
technical
assay
≥95% (HPLC)
mp
245 °C (dec.) (lit.)
SMILES string
Oc1cccnc1O
InChI
1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)
InChI key
GGOZGYRTNQBSSA-UHFFFAOYSA-N
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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The first mu(6)-peroxide transition-metal complex: [Ni(8)(L)(12)(O(2))](2+).
Emma J Brown et al.
Angewandte Chemie (International ed. in English), 44(9), 1392-1395 (2005-01-05)
A al-Dehneh et al.
Journal of animal science, 72(2), 415-420 (1994-02-01)
Sixteen Alpine wethers (average BW 35 +/- 2 kg) were used to evaluate the effect of continuous 48-h intravenous infusions of saline (CON), mimosine (MIM; 200 mg.kg.75.d-1), 2-hydroxy-3(1H)-pyridine (2,3-DHP; 200 mg.kg.75.d-1, or MIM+2,3-DHP (100 mg of MIM plus 100 mg
M J Raxworthy et al.
Biochemical pharmacology, 32(8), 1361-1364 (1983-04-15)
Despite its structural similarity to catechol, 2,3-dihydroxypyridine is not a substrate but a "dead-end" inhibitor of purified pig liver catechol-O-methyltransferase. It inhibits the methylation of 3,4-dihydroxyphenylacetic acid competitively with an inhibitor constant of 15 microM. Against the methyl donor, S-adenosyl-L-methionine
T Sahlu et al.
Journal of animal science, 73(1), 172-176 (1995-01-01)
Sixteen growing Alpine wethers (average BW 35 +/- 2 kg) were assigned to one of four treatments to evaluate tissue retention of the leucaena toxins mimosine (MIM) and 2,3-dihydroxypyridine (2,3-DHP). Treatments were infused i.v. for 2 d and were 1)
Antithyroid effect of 2,3-dihydroxypyridine in vivo and in vitro.
M Sugawara et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 170(4), 431-435 (1982-09-01)
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