38490
5,5-Dimethyl-1,3-cyclohexanedione
derivatization grade (HPLC), for the determination of aldehyde formaldehyde, ≥99.0%
Synonym(s):
Dimedone, Methone
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About This Item
Linear Formula:
(CH3)2C6H6(=O)2
CAS Number:
Molecular Weight:
140.18
UNSPSC Code:
12164500
NACRES:
NA.21
PubChem Substance ID:
EC Number:
204-804-4
Beilstein/REAXYS Number:
471489
MDL number:
Assay:
≥99.0% (GC), ≥99.0%
InChI key
BADXJIPKFRBFOT-UHFFFAOYSA-N
InChI
1S/C8H12O2/c1-8(2)4-6(9)3-7(10)5-8/h3-5H2,1-2H3
SMILES string
CC1(C)CC(=O)CC(=O)C1
grade
derivatization grade (HPLC)
assay
≥99.0% (GC), ≥99.0%
quality
for the determination of aldehyde formaldehyde
Quality Level
application(s)
general analytical
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General description
5,5-dimethyl-1,3-cyclohexanedione (Dimedone) is basically a highly sensitive and very specific reagent used for the determination of aldehydes. It is highly advantageous as it is environment friendly, give high yields and is a simple workup procedure.
Application
5,5-dimethyl-1,3-cyclohexanedione may be used in condensation reaction with aromatic aldehyde in ethylene glycol. It may be also be used in trace analysis of aldehydes by HPLC.
flash_point_f
Not applicable
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Jesse C Patterson et al.
Cell systems, 8(2), 163-167 (2019-02-25)
Although elevated levels of reactive oxygen species (ROS) have been observed in cancer cells and cancer cells aberrantly proliferate, it is not known whether the level of reactive oxygen species and the accumulation of oxidative damage to macromolecules vary across
Trace analysis of aldehydes by reversed-phase high-performance liquid chromatography and precolumn fluorigenic labeling with 5, 5-dimethyl-1, 3-cyclohexanedione.
Kenneth M
Journal of Chromatography A, 256, 243-252 (1983)
Solid-State Condensation Reactions Between Aldehydes and 5, 5-Dimethyl-1, 3-cyclohexanedione by Grinding at Room Temperature.
Tong-shou J
Synthetic Communications, 35 (17), 2339-2345 (2005)
Condensation of aromatic aldehydes with 5, 5-dimethyl-1, 3-cyclohexanedione without catalyst.
Shujiang Tu
Synthetic Communications, 32 (19), 3063-3067 (2002)
Joseph R Burgoyne et al.
Biochemical Society transactions, 39(5), 1260-1267 (2011-09-23)
Elevated protein oxidation is a widely reported hallmark of most major diseases. Historically, this 'oxidative stress' has been considered causatively detrimental, as the protein oxidation events were interpreted simply as damage. However, recent advances have changed this antiquated view; sensitive
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