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Merck
CN

39339

3-(Dimethylamino)propionitrile

suitable for electrophoresis, ≥99.5% (GC)

Synonym(s):

DMAPN

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About This Item

Linear Formula:
(CH3)2NCH2CH2CN
CAS Number:
Molecular Weight:
98.15
EC Number:
217-090-4
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
773779
MDL number:
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assay

≥99.5% (GC)

technique(s)

electrophoresis: suitable

impurities

≤0.2% water

refractive index

n20/D 1.426

bp

171 °C/750 mmHg (lit.)

mp

−43 °C (lit.)

density

0.87 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

suitability

in accordance for electrophoresis test

SMILES string

CN(C)CCC#N

InChI

1S/C5H10N2/c1-7(2)5-3-4-6/h3,5H2,1-2H3

InChI key

MTPJEFOSTIKRSS-UHFFFAOYSA-N

Application

Catalyst similar to TEMED used to form oxygen free radicals from ammonium persulfate. Free radicals cause acrylamide and bis-acrylamide to polymerize.

Other Notes

Purification of RNA molecules by gel techniques


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

145.4 °F - closed cup

flash_point_c

63 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Purification of RNA molecules by gel techniques.
T Ikemura
Methods in enzymology, 180, 14-25 (1989-01-01)
M M Mumtaz et al.
Journal of toxicology and environmental health, 33(1), 1-17 (1991-05-01)
N,N'-Dimethylaminopropionitrile (DMAPN), a major component of the NIAX catalyst ESN, is known to cause urinary bladder dysfunction in exposed workers. In order to investigate the mechanism of DMAPN toxicity, we carried out time-course (0-72 h) and dose-response (175-700 mg/kg) studies
Inhibition of acetylcholinesterase by neurotoxic aminonitriles.
J R Froines
Biochemical pharmacology, 34(17), 3185-3187 (1985-09-01)