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Merck
CN

398144

Nitrilotriacetic acid

ACS reagent, ≥98%

Synonym(s):

N,N-Bis(carboxymethyl)glycine, NTA, Tris(carboxymethyl)amine

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About This Item

Linear Formula:
N(CH2COOH)3
CAS Number:
Molecular Weight:
191.14
EC Number:
205-355-7
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1710776
MDL number:
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grade

ACS reagent

assay

≥98%

mp

245 °C (dec.) (lit.)

suitability

suitable for suitability for complexometry

SMILES string

OC(=O)CN(CC(O)=O)CC(O)=O

InChI

1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)

InChI key

MGFYIUFZLHCRTH-UHFFFAOYSA-N

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Application

An excellent chelating agent.

signalword

Warning

pictograms

Health hazardExclamation mark

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

212.0 °F - closed cup

flash_point_c

100 °C - closed cup

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Matti F Pronker et al.
The Journal of biological chemistry, 290(24), 15092-15101 (2015-04-24)
Olfactomedin-1 (Olfm1; also known as noelin and pancortin) is a member of the olfactomedin domain-containing superfamily and a highly expressed neuronal glycoprotein important for nervous system development. It binds a number of secreted proteins and cell surface-bound receptors to induce
Li Jiang et al.
The Journal of pathology, 228(3), 366-377 (2012-08-07)
Exposure to asbestos is a risk for malignant mesothelioma (MM) in humans. Among the commercially used types of asbestos (chrysotile, crocidolite, and amosite), the carcinogenicity of chrysotile is not fully appreciated. Here, we show that all three asbestos types similarly
Hui Xu et al.
Biosensors & bioelectronics, 41, 90-95 (2012-09-11)
A label-free and highly sensitive impedimetric aptasensor was developed based on electropolymerized film for the determination of thrombin. The first step is the electrogeneration of a poly(pyrrole-nitrilotriacetic acid) (poly(pyrrole-NTA)) film onto the surface of electrodes followed by complexation of Cu(2+)
R L Anderson et al.
Critical reviews in toxicology, 15(1), 1-102 (1985-01-01)
This article provides a review of available information on the chemistry, environmental toxicology, and mammalian toxicology of nitrilotriacetic acid (NTA). The ability of NTA to chelate metal ions such as Mg++ and Ca++ into water soluble complexes makes NTA useful
Asgar Abbas Kazrani et al.
Nucleic acids research, 42(9), 5929-5936 (2014-03-19)
PvuRts1I is a prototype for a larger family of restriction endonucleases that cleave DNA containing 5-hydroxymethylcytosine (5hmC) or 5-glucosylhydroxymethylcytosine (5ghmC), but not 5-methylcytosine (5mC) or cytosine. Here, we report a crystal structure of the enzyme at 2.35 Å resolution. Although

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