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Merck
CN

403032

Sodium arsenate dibasic heptahydrate

ACS reagent, ≥98%

Synonym(s):

Disodium hydrogen arsenate heptahydrate, Sodium hydrogenarsenate heptahydrate

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About This Item

Linear Formula:
Na2HAsO4 · 7H2O
CAS Number:
Molecular Weight:
312.01
UNSPSC Code:
12352300
MDL number:
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grade

ACS reagent

assay

≥98%, 98.0-102.0% (ACS specification)

impurities

≤0.005% insolubles, ≤0.01% As2O3

mp

180 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤0.001%, nitrate (NO3-): ≤0.005%, sulfate (SO42-): ≤0.01%

cation traces

Fe: ≤0.001%, heavy metals (as Pb): ≤0.002%

SMILES string

[Na+].[Na+].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].O[As]([O-])([O-])=O

InChI

1S/AsH3O4.2Na.7H2O/c2-1(3,4)5;;;;;;;;;/h(H3,2,3,4,5);;;7*1H2/q;2*+1;;;;;;;/p-2

InChI key

KOLXPEJIBITWIQ-UHFFFAOYSA-L

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Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Shugo Suzuki et al.
Toxicology, 299(2-3), 155-159 (2012-06-06)
Inorganic arsenic is a known human carcinogen, inducing tumors of the skin, urinary bladder and lung. It is metabolized to organic methylated arsenicals. 2,3-Dimercaptopropane-1-sulfonic acid (DMPS), a chelating agent, is capable of reducing pentavalent arsenicals to the trivalent state and
Dae Hyun Baek et al.
Journal of applied toxicology : JAT, 32(8), 617-626 (2011-12-02)
The embryonic stem cell test (EST) is a validated in vitro embryotoxicity test; however, as the inhibition of cardiac differentiation alone is used as a differentiation endpoint in the EST, it may not be a useful test to screen embryotoxic
Takayuki Watanabe et al.
Archives of toxicology, 85(6), 577-588 (2011-05-04)
It has been suggested that arsenic (+3 oxidation state) methyltransferase (AS3MT) plays a critical role in methylation of arsenic, and that arsenic-glutathione conjugate is a substrate for AS3MT-catalyzed methylation of arsenic. However, the mechanism of arsenic methylation in cells is
Deniz Yildiz et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 26(1), 53-58 (2011-12-20)
The objective of the present study was to investigate if arsenate V exposure results in glutathione efflux from human erythrocytes. The changes in intracellular and extracellular nonprotein sulfhydryl and glutathione levels were determined in arsenate (V) exposed erythrocytes. Presence of
Mark J Canet et al.
Drug metabolism and disposition: the biological fate of chemicals, 40(9), 1817-1824 (2012-06-16)
Nonalcoholic fatty liver disease (NAFLD) is represented by a spectrum of liver pathologies ranging from simple steatosis to nonalcoholic steatohepatitis (NASH). Liver damage sustained in the progressive stages of NAFLD may alter the ability of the liver to properly metabolize

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