40404
1,1-Dimethylguanidine sulfate salt
purum, ≥98.0% (NT)
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About This Item
Linear Formula:
[(CH3)2NC(NH2)=NH]2 · H2SO4
CAS Number:
Molecular Weight:
272.33
EC Number:
209-946-0
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
3916505
MDL number:
InChI key
QSCHFHVDZCPIKX-UHFFFAOYSA-N
InChI
1S/2C3H9N3.H2O4S/c2*1-6(2)3(4)5;1-5(2,3)4/h2*1-2H3,(H3,4,5);(H2,1,2,3,4)
SMILES string
OS(O)(=O)=O.CN(C)C(N)=N.CN(C)C(N)=N
grade
purum
assay
≥98.0% (NT)
mp
300 °C (dec.) (lit.)
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W Zhang et al.
Acta physiologica Scandinavica, 159(1), 1-6 (1997-01-01)
1,1-dimethylguanidine (DMG) is an endogenous nitric oxide (NO) synthesis inhibitor. This study investigates the effects of exogenous DMG administration, in anaesthetized spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). Mean blood pressure (MBP), heart rate (HR) and renal sympathetic nerve
R Sopio et al.
Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 201(4), 381-386 (1995-10-01)
Deoxyosones are established key-intermediates in Maillard processes. Due to their dicarbonyl structure, they undergo condensation to form heterocyclic compounds with guanidine derivatives. In biological systems, guanidino functions are present in protein-bound arginine moieties as well as in creatine. The reactivity
J A Hirsch
The Journal of pharmacology and experimental therapeutics, 230(3), 710-717 (1984-09-01)
The effect of guanidine alkyl derivatives on the evoked release of [3H]norepinephrine [( 3H]NE) from spleen strips was examined. Guanidine, methyl guanidine and N,N-dimethyl guanidine all enhanced the field-stimulated release of [3H]NE 2- to 3-fold, whereas N,N'-dimethyl guanidine and propyl
E Benoit
Receptors & channels, 1(3), 181-191 (1993-01-01)
The effects of guanidine and dimethyl guanidine were studied on current- and voltage-clamped nodes of Ranvier, to determine the electrophysiological basis for the guanidine-induced increase in neurotransmitter release. When added to the external solution, guanidine produced positive shifts of K
D J Wolff et al.
Archives of biochemistry and biophysics, 325(2), 227-234 (1996-01-15)
Diaminoguanidine (DAG) and NG-amino-L-arginine each produced a time- and concentration-dependent inactivation of the citrulline-forming activity of all three NOS isoforms. DAG inactivates both the NADPH-oxidase and the citrulline-forming activities of GH3 pituitary nNOS while NG-amino-L-arginine inactivates only its citrulline-forming activity.
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