Skip to Content
Merck
CN

40765

(−)-Tröger′s base

LiChropur™, ≥99.0%

Synonym(s):

(5R,11R)-(−)-2,8-Dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocin

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C17H18N2
CAS Number:
14645-24-0
Molecular Weight:
250.34
PubChem Substance ID:
329755941
UNSPSC Code:
41116105
Beilstein/REAXYS Number:
88611
MDL number:
MFCD00151117

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

SMILES string

Cc1ccc2[N@@H]3C[N@H](Cc2c1)c4ccc(C)cc4C3

InChI

1S/C17H18N2/c1-12-3-5-16-14(7-12)9-18-11-19(16)10-15-8-13(2)4-6-17(15)18/h3-8H,9-11H2,1-2H3

InChI key

SXPSZIHEWFTLEQ-UHFFFAOYSA-N

grade

derivatization grade ((chiral))

assay

≥99.0% (sum of enantiomers, HPLC), ≥99.0%

optical activity

[α]20/D −283±4°, c = 0.3% in hexane

optical purity

enantiomeric ratio: ≥99.5:0.5 (HPLC)

quality

LiChropur™

mp

127-131 °C

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

General description

Tröger base (TB) is a chiral heterocyclic amine with chirality due to the presence of two stereogenic nitrogen atoms.

Application

It was used as an standard analyte for testing the enantioseparation capability of the chiral stationary phase column; in a study to understand the covalently bonded cellulose tris(3,5-dimethylphenylcarbamate) on a silica monolithic capillary column.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Xiaoli Dong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 875(1), 317-322 (2008-09-02)
A chiral capillary monolithic column for capillary electrochromatography (CEC) was prepared by covalent bonding of cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC) on the silica monolithic matrix within the confine of a 50-microm i.d. bare fused silica capillary. Several pairs of enantiomers including neutral
Resolution, asymmetric transformation, and configuration of Troger's base. Application of Troger's base as a chiral solvating agent.
Wilen, Samuel H., Jian Zhong Qi, and Paul G. Williard
Organic Chemistry, 56, 485-487 (1991)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service