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Merck
CN

41278

(S)-Thiolactic acid

Synonym(s):

(S)-2-Mercaptopropionic acid

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About This Item

Empirical Formula (Hill Notation):
C3H6O2S
CAS Number:
Molecular Weight:
106.14
PubChem Substance ID:
MDL number:
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InChI key

PMNLUUOXGOOLSP-REOHCLBHSA-N

InChI

1S/C3H6O2S/c1-2(6)3(4)5/h2,6H,1H3,(H,4,5)/t2-/m0/s1

SMILES string

C[C@H](S)C(O)=O

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

233.6 °F - closed cup

flash_point_c

112 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

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Glen G Briand et al.
Inorganic chemistry, 43(20), 6495-6500 (2004-09-28)
Although bismuth compounds have been used in medicine for over 200 years, chemical characterization of complexes involving biological molecules is minimal and mechanisms of bioactivity are ill-defined. The thiophilic nature of bismuth implicates sulfur centers as likely sites for interaction
P Leroy et al.
Journal of chromatography, 564(1), 258-265 (1991-03-08)
A simple and fast high-performance liquid chromatographic method was developed for the simultaneous measurement of 2-mercaptopropionylglycine (Tiopronine) and its metabolite (2-mercaptopropionic acid) in human plasma after the administration of a pharmaceutical dosage form (Acadione). The sample treatment before high-performance liquid
Sumru Ozkirimli et al.
Journal of enzyme inhibition and medicinal chemistry, 24(2), 447-452 (2008-11-13)
A new series of 3-(1,2,4-triazol-3-yl)-4-thiazolidinone derivatives has been synthesized by the reaction of Schiff bases of 3-amino-1,2,4-triazoles with mercaptoacetic acid and 2-mercaptopropionic acid. Their antibacterial and antifungal activities were evaluated against S. aureus, S. epidermidis, C. albicans and C. glabrata.
Studies on heterocyclic compounds: 1,3-thiazolidin-4-ones from Schiff bases.
E Piscopo et al.
Bollettino della Societa italiana di biologia sperimentale, 64(2), 153-158 (1988-02-01)
B Hercelin et al.
European journal of clinical pharmacology, 43(1), 93-95 (1992-01-01)
We have studied the pharmacokinetics of tiopronin and its principal metabolite, 2-mercaptopropionic acid (2-MPA) in healthy volunteers after the oral administration of 500 mg (2 Acadione tablets), followed by simultaneous assay of the two compounds in plasma over a period

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