42670
Diphenic acid
technical, ≥95% (T)
Synonym(s):
Biphenyl-2,2′-dicarboxylic acid
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About This Item
Linear Formula:
2-(HO2C)C6H4C6H4-2-(CO2H)
CAS Number:
Molecular Weight:
242.23
EC Number:
207-576-4
UNSPSC Code:
12162002
PubChem Substance ID:
Beilstein/REAXYS Number:
2053625
MDL number:
grade
technical
assay
≥95% (T)
ign. residue
≤1%
mp
227-229 °C (lit.), 229-232 °C
SMILES string
OC(=O)c1ccccc1-c2ccccc2C(O)=O
InChI
1S/C14H10O4/c15-13(16)11-7-3-1-5-9(11)10-6-2-4-8-12(10)14(17)18/h1-8H,(H,15,16)(H,17,18)
InChI key
GWZCCUDJHOGOSO-UHFFFAOYSA-N
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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K A Ohemeng et al.
Journal of medicinal chemistry, 40(20), 3292-3296 (1997-11-05)
The synthesis and inhibitory activity against DNA gyrase of a series of diphenic acid monohydroxamides 4a-f are described. A protocol of two biological assays showed conclusively that inhibition occurs specifically at the DNA-DNA gyrase complex and is not attributable to
Masashi Kunitake et al.
Langmuir : the ACS journal of surfaces and colloids, 21(20), 9206-9210 (2005-09-21)
Formation of adlayers of the optically active compound 1,1'-binaphthyl-2, 2'-dicarboxylic acid (BINAC) on iodine-modified Au (111) surfaces in perchloric acid was investigated by in situ scanning tunneling microscopy (STM). Highly ordered arrays formed on the surfaces via simple spontaneous adsorption
K E Hammel et al.
Applied and environmental microbiology, 58(6), 1832-1838 (1992-06-01)
The ligninolytic fungus Phanerochaete chrysosporium oxidized phenanthrene and phenanthrene-9,10-quinone (PQ) at their C-9 and C-10 positions to give a ring-fission product, 2,2'-diphenic acid (DPA), which was identified in chromatographic and isotope dilution experiments. DPA formation from phenanthrene was somewhat greater
F H Clarke et al.
Journal of pharmaceutical sciences, 76(8), 611-620 (1987-08-01)
A convenient procedure has been developed for the determination of partition and distribution coefficients. The method involves the potentiometric titration of the compound, first in water and then in a rapidly stirred mixture of water and octanol. An automatic titrator
Xiang-Wen Kong et al.
Chemistry & biodiversity, 5(9), 1743-1752 (2008-09-26)
In search of novel anticancer agents, two series of dimethyl [1,1'-biphenyl]-2,2'-dicarboxylate derivatives, 8a-8k and 9a-9k, containing both methylenedioxy and 1,3,4-thiadiazole moieties were designed and synthesized. Cytotoxicity of these compounds was evaluated in vitro against five human tumor cell lines, i.e.
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