42880
Diphenylmethanol
puriss., ≥99.0% (GC)
Synonym(s):
Benzhydrol, Benzhydryl alcohol, Diphenyl carbinol
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About This Item
Linear Formula:
(C6H5)2CHOH
CAS Number:
Molecular Weight:
184.23
EC Number:
202-033-8
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1424379
MDL number:
InChI key
QILSFLSDHQAZET-UHFFFAOYSA-N
InChI
1S/C13H12O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13-14H
SMILES string
OC(c1ccccc1)c2ccccc2
grade
puriss.
assay
≥99.0% (GC)
bp
297-298 °C (lit.)
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Storage Class
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Alkylation of alcohols for gas chromatographic analysis by a phase transfer catalysis technique. Evaluation of benzhydrol benzylation in a one-phase system.
H Brink et al.
Acta pharmaceutica Suecica, 16(4), 247-262 (1979-01-01)
Masanori Ichikawa et al.
Bioorganic & medicinal chemistry, 20(9), 3072-3093 (2012-04-03)
In the present article, we have reported the design, synthesis, and identification of highly potent benzhydrol derivatives as squalene synthase inhibitors (compound 1). Unfortunately, the in vivo efficacies of the compounds were not enough for acquiring the clinical candidate. We
Xiao-Dong Ma et al.
Bioorganic & medicinal chemistry, 19(16), 4704-4709 (2011-07-27)
A series of (±)-benzhydrol derivatives featuring the essential sulfonamide group at the para position on the C-ring were synthesized and evaluated for the potential anti-HIV activity in C8166 cells. Most of these analogues demonstrated low concentration inhibitory activity with EC(50)
Kinetics of the hydrolysis of drugs containing the diphenyl-methyl-ether group.
O O Komolafe
Materia medica Polona. Polish journal of medicine and pharmacy, 17(2), 98-102 (1985-04-01)
[Determination of dimedrol and benzhydrol in the urine by high efficient liquid chromatographic method].
E N Stepanova et al.
Sudebno-meditsinskaia ekspertiza, 23(2), 40-42 (1980-04-01)
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