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Merck
CN

43030

1,3-Diphenylguanidine

purum, ≥98.0% (NT)

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About This Item

Linear Formula:
(C6H5NH)2C=NH
CAS Number:
Molecular Weight:
211.26
EC Number:
203-002-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1875653
MDL number:
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InChI key

OWRCNXZUPFZXOS-UHFFFAOYSA-N

InChI

1S/C13H13N3/c14-13(15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H,(H3,14,15,16)

SMILES string

N=C(Nc1ccccc1)Nc2ccccc2

grade

purum

assay

≥98.0% (NT)

Gene Information

human ... EPHX2(2053)
mouse ... Ephx2(13850)
rat ... Grin2a(24409), Scnn1g(24768)

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Regulatory Information

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Mingxiang Lin et al.
Journal of pharmaceutical and biomedical analysis, 45(5), 747-755 (2007-10-12)
During the content uniformity test of a drug product (tablet formulation), an unknown peak was observed in the HPLC chromatograms. Upon further investigation, it was determined that the unknown peak was originated from an external source and, therefore, the drug
Allergy to rubber additives in orthopedic braces.
S T Bolhaar et al.
Contact dermatitis, 42(5), 288-289 (2000-05-02)
Occupational allergic contact dermatitis from diphenylguanidine in a gas mask.
M Bruze et al.
Contact dermatitis, 31(2), 125-126 (1994-08-01)
P V Shah et al.
Journal of toxicology and environmental health, 15(5), 623-633 (1985-01-01)
Dermal absorption, distribution, and metabolism of 1,3-diphenylguanidine (CAS 102-06-7) (DPG), widely used as an accelerator in processing rubber and in food packaging, was studied in adult female Sprague-Dawley rats. DPG shows 10% penetration through clipped back skin of the rats
M A Bempong et al.
Journal of toxicology and environmental health, 11(4-6), 869-878 (1983-04-01)
The effects of 1,3-diphenylguanidine (DPG) on seminal cytology in hybrid mice and inbred Syrian golden hamsters and on testicular histology and reproductive toxicity in mice were monitored. Treatment consisted of chronic exposure of hamsters and mice to DPG in 0.025%

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