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Merck
CN

43182

α,α-Diphenyl-L-prolinol

purum, ≥99.0% (sum of enantiomers, HPLC)

Synonym(s):

(S)-α,α-Diphenyl-2-pyrrolidinemethanol, (S)-2-(Diphenylhydroxymethyl)pyrrolidine

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About This Item

Empirical Formula (Hill Notation):
C17H19NO
CAS Number:
Molecular Weight:
253.34
UNSPSC Code:
12352000
MDL number:
Beilstein/REAXYS Number:
6060893
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grade

purum

assay

≥99.0% (sum of enantiomers, HPLC)

optical activity

[α]20/D −69±2°, c = 3% in chloroform

optical purity

enantiomeric ratio: ≥99.5:0.5 (HPLC)

mp

77-80 °C

SMILES string

OC([C@@H]1CCCN1)(c2ccccc2)c3ccccc3

Other Notes

The cyclic borane adduct, an oxazaborolidine, is an efficient catalyst for enantioselective reductions of ketones with borane (CBS-reduction)

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

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M. Periasamy
Pure and Applied Chemistry. Chimie Pure Et Appliquee, 68, 663-663 (1996)
J.V.B. Kanth, H.C. Brown
Tetrahedron, 58, 1069-1069 (2002)
D.J. Mathre et al.
The Journal of Organic Chemistry, 58, 2880-2880 (1993)
E.J. Corey et al.
Tetrahedron Letters, 31, 611-611 (1990)

Global Trade Item Number

SKUGTIN
86652-50G04061833552490
86652-10G04061834412274

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