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Merck
CN

43765

2,2′-Dithiobis(5-nitropyridine)

≥97.0% (HPLC)

Synonym(s):

Bis(5-nitro-2-pyridyl) disulfide, DTNP

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About This Item

Empirical Formula (Hill Notation):
C10H6N4O4S2
CAS Number:
Molecular Weight:
310.31
EC Number:
218-344-7
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
305413
MDL number:
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assay

≥97.0% (HPLC)

mp

152-154 °C, 155-157 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(SSc2ccc(cn2)[N+]([O-])=O)nc1

InChI

1S/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6H

InChI key

ROUFCTKIILEETD-UHFFFAOYSA-N

Other Notes

Selective reagent for the detection of thiols; Inhibitor of ATPase of chloroplast coupling factor 1

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R H Vallejos et al.
Biochimica et biophysica acta, 459(1), 20-26 (1977-01-06)
1. O-Iodosobenzoate and 2,2'-dithio bis-(5-nitropyridine) inhibited by about fifty per cent the ATPase activity of heat-activated chloroplast coupling factor 1 only when present during the heating but were without effect when added before or after the activation. Reversion of this
Determining simple sulfhydryl compounds (low molecular weight) and their contents in biological samples by using 2,2'-dithiobis-(5-nitropyridine).
A Swatditat et al.
Analytical biochemistry, 45(2), 349-356 (1972-02-01)
The use of 2,2'-dithiobis-(5-nitropyridine) as a selective reagent for the detection of thiols.
D R Grassetti et al.
Journal of chromatography, 41(1), 121-123 (1969-04-22)

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