44699
Rosmarinic acid
purum, ≥95.0% (HPLC)
Synonym(s):
(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester
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About This Item
Empirical Formula (Hill Notation):
C18H16O8
CAS Number:
Molecular Weight:
360.31
UNSPSC Code:
12352000
Beilstein/REAXYS Number:
2227587
MDL number:
grade
purum
assay
≥95.0% (HPLC)
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
171-175 °C
SMILES string
OC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)\C=C\c2ccc(O)c(O)c2
InChI
1S/C18H16O8/c19-12-4-1-10(7-14(12)21)3-6-17(23)26-16(18(24)25)9-11-2-5-13(20)15(22)8-11/h1-8,16,19-22H,9H2,(H,24,25)/b6-3+/t16-/m1/s1
InChI key
DOUMFZQKYFQNTF-WUTVXBCWSA-N
Biochem/physiol Actions
Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive performance, Alzheimer′s disease prevention, kideney disease treatment, cardioprotection and cancer chemoprevention.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Bo Liang et al.
BMC complementary medicine and therapies, 20(1), 345-345 (2020-11-15)
Guanxin V (GXV), a traditional Chinese medicine (TCM), has been widely used to treat coronary artery disease (CAD) in clinical practice in China. However, research on the active components and underlying mechanisms of GXV in CAD is still scarce. A
Vivek Swarup et al.
Antimicrobial agents and chemotherapy, 51(9), 3367-3370 (2007-06-20)
Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels
Mélanie Dubois et al.
Journal of medicinal chemistry, 51(8), 2575-2579 (2008-03-21)
Rosmarinic acid was reacted with nitrite ions under acidic conditions to give 6'-nitro- and 6',6''-dinitrorosmarinic acids according to the reaction time. Both compounds were active as HIV-1 integrase inhibitors at the submicromolar level. They also inhibited the viral replication in