45140
Ellagic acid
≥96.0% (HPCE)
Synonym(s):
4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase
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About This Item
Empirical Formula (Hill Notation):
C14H6O8
CAS Number:
Molecular Weight:
302.19
EC Number:
207-508-3
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
47549
MDL number:
InChI key
AFSDNFLWKVMVRB-UHFFFAOYSA-N
InChI
1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
SMILES string
Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
assay
≥96.0% (HPCE)
impurities
<12% water
mp
≥350 °C
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Biochem/physiol Actions
Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma. Contact activation in blood coagulation.
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Qingqing Tian et al.
Theranostics, 10(9), 4101-4115 (2020-04-01)
Rationale: Chemodynamic therapy (CDT) based on the Fe(II)-mediated Fenton reaction is an emerging tumor treatment strategy. However, the catalytic efficiency in tumors is crucially limited by Fe(II). Herein, an endogenous hydrogen sulfide (H2S) accelerated Fe(III)/Fe(II) transformation and photothermal synergistically enhanced
Giorgio Cozza et al.
Journal of medicinal chemistry, 49(8), 2363-2366 (2006-04-14)
Casein kinase 2 (CK2) is a ubiquitous, essential, and highly pleiotropic protein kinase whose abnormally high constitutive activity is suspected to underlie its pathogenic potential in neoplasia and other diseases. Using a virtual screening approach, we have identified the ellagic
Navindra P Seeram et al.
Clinica chimica acta; international journal of clinical chemistry, 348(1-2), 63-68 (2004-09-17)
Ellagic acid (EA) and hydrolyzable ellagitannins (ETs) are dietary polyphenols found in fruits and nuts and implicated with potent antioxidant, anticancer and antiatherosclerotic biological properties. Unfortunately, there are no reports on the bioavailability studies of EA or ETs in the
Felipe Jimenez et al.
The Journal of investigative dermatology, 126(6), 1272-1280 (2006-04-08)
Progressive proteolytic degradation of cutaneous elastic fibers, that cannot be adequately replaced or repaired by adult dermal fibroblasts, constitutes a major feature of aging skin. Our present investigations, employing monolayer cultures of human dermal fibroblasts and organ cultures of skin
J-T Banzouzi et al.
Journal of ethnopharmacology, 81(3), 399-401 (2002-07-20)
Extracts of leaves of Alchornea cordifolia were studied for their antiplasmodial activities. Chloroformic and ether extracts were found to be inactive while the ethanolic extract exhibited mild in vitro activity against Plasmodium falciparum. Fractionation of this extract led us to
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