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Merck
CN

46002

Sigma-Aldrich

4-Methylumbelliferyl acetate

Synonym(s):

MU-Ac

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About This Item

Empirical Formula (Hill Notation):
C12H10O4
CAS Number:
Molecular Weight:
218.21
Beilstein:
189667
EC Number:
MDL number:
UNSPSC Code:
12352204
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mp

149-150 °C (lit.)

solubility

DMF: soluble
DMSO: soluble

fluorescence

λex 365 nm; λem 445 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

CC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3

InChI key

HXVZGASCDAGAPS-UHFFFAOYSA-N

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Other Notes

Fluorogenic substrate for esterases; Measurement of intracellular pH in rat proximal convoluted tubule

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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E Pastoriza-Munoz et al.
The Journal of clinical investigation, 80(1), 207-215 (1987-07-01)
In the proximal convoluted tubule (PT), the HCO3- reabsorptive rate is higher in early (EPS) compared with late proximal segments (LPS). To examine the mechanism of this HCO3- reabsorption profile, intracellular pH (pHi) was measured along the superficial PT of
C Dive et al.
Cytometry, 8(6), 552-561 (1987-11-01)
Flow cytoenzymology is the determination of enzyme activities or concentrations in single intact cells. Using the flow cytometer built and designed in our laboratory and recent modifications to hardware and software, we have developed an improved dynamic flow cytoenzymological procedure

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