46002
4-Methylumbelliferyl acetate
Synonym(s):
MU-Ac
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About This Item
Empirical Formula (Hill Notation):
C12H10O4
CAS Number:
Molecular Weight:
218.21
EC Number:
220-386-6
UNSPSC Code:
12352204
MDL number:
Beilstein/REAXYS Number:
189667
InChI
1S/C12H10O4/c1-7-5-12(14)16-11-6-9(15-8(2)13)3-4-10(7)11/h3-6H,1-2H3
InChI key
HXVZGASCDAGAPS-UHFFFAOYSA-N
SMILES string
CC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1
mp
149-150 °C (lit.)
solubility
DMF: soluble, DMSO: soluble
fluorescence
λex 365 nm; λem 445 nm in 0.1 M Tris pH 8.0 (esterase)
suitability
suitable for fluorescence
storage temp.
−20°C
Other Notes
Fluorogenic substrate for esterases; Measurement of intracellular pH in rat proximal convoluted tubule
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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C Dive et al.
Cytometry, 8(6), 552-561 (1987-11-01)
Flow cytoenzymology is the determination of enzyme activities or concentrations in single intact cells. Using the flow cytometer built and designed in our laboratory and recent modifications to hardware and software, we have developed an improved dynamic flow cytoenzymological procedure
E Pastoriza-Munoz et al.
The Journal of clinical investigation, 80(1), 207-215 (1987-07-01)
In the proximal convoluted tubule (PT), the HCO3- reabsorptive rate is higher in early (EPS) compared with late proximal segments (LPS). To examine the mechanism of this HCO3- reabsorption profile, intracellular pH (pHi) was measured along the superficial PT of
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