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Merck
CN

46149

Supelco

Corticosterone 21-acetate

VETRANAL®, analytical standard

Synonym(s):

11β,21-Dihydroxy-4-pregnene-3,20-dione 21-acetate, 4-Pregnene-11β,21-diol-3,20-dione 21-acetate

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About This Item

Empirical Formula (Hill Notation):
C23H32O5
CAS Number:
1173-26-8
Molecular Weight:
388.50
Beilstein:
3225312
EC Number:
214-635-8
MDL number:
MFCD00010482
UNSPSC Code:
41116107
PubChem Substance ID:
329757088
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]4(C)[C@H](CC[C@@]24[H])C(=O)COC(C)=O

InChI

1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1

InChI key

WKQCPUMQBMFPLC-ZWFCQKKLSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCBW2963

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Fengxia Yan et al.
International journal of biological sciences, 16(15), 2775-2787 (2020-10-17)
FoxO3a, a forkhead family member of transcription factors, is involved in the regulation of cell metabolism, proliferation, differentiation and apoptosis. However, whether FoxO3a participates in the regulation of glucocorticoids induced-hypothalamic-pituitary-adrenal (HPA) dysfunction is still unknown. Our present results indicate that
J T Vreeburg et al.
Journal of steroid biochemistry, 29(1), 93-98 (1988-01-01)
Corticosterone acetate (10 mg/day) was administered to gonadectomized and adrenalectomized male rats bearing 5, 10 or 15 mm long testosterone filled silicone elastomer capsules. It was found that the serum testosterone levels induced by these capsules were not influenced by
H Okahata et al.
Acta endocrinologica, 111(4), 539-545 (1986-04-01)
The effects of weaning (abrupt dietary changes from breast milk to solid food) and corticosterone injection on antral gastrin-like immunoreactivity (G-LI) concentrations and antral G-LI biosynthesis were studied in rats. A single dose of corticosterone acetate was injected in one
B R Sankar et al.
The Journal of steroid biochemistry and molecular biology, 72(3-4), 155-162 (2000-04-25)
The mechanism involved in the inhibitory actions of chronic corticosterone treatment on Leydig cell steroidogenesis was studied in adult Wistar rats. Rats were treated with corticosterone-21-acetate (2 mg/100 g body weight, i.m., twice daily) for 15 days and another set
D Filipini et al.
The Journal of steroid biochemistry and molecular biology, 39(2), 245-252 (1991-08-01)
The effects of various steroid hormones on the long-term potentiation (LTP) of the rat hippocampus were evaluated. LTP was elicited in the dentate gyrus of adrenalectomized animals with priming tetanic stimulation (200 Hz-0.03 cps) of its main afferent, the perforant
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