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Merck
CN

46149

Corticosterone 21-acetate

VETRANAL®, analytical standard

Synonym(s):

11β,21-Dihydroxy-4-pregnene-3,20-dione 21-acetate, 4-Pregnene-11β,21-diol-3,20-dione 21-acetate

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About This Item

Empirical Formula (Hill Notation):
C23H32O5
CAS Number:
1173-26-8
Molecular Weight:
388.50
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757088
EC Number:
214-635-8
Beilstein/REAXYS Number:
3225312
MDL number:
MFCD00010482

Key Documents

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Quality Level

100

InChI key

WKQCPUMQBMFPLC-ZWFCQKKLSA-N

InChI

1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]4(C)[C@H](CC[C@@]24[H])C(=O)COC(C)=O

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCBW2963

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L E Flores et al.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 120(1), 77-81 (1998-11-25)
The aim of this work was to demonstrate the possible direct effect of several hormones upon glucose-induced insulin secretion in amphibians. Hence, pancreas pieces of Bufo arenarum were incubated for 60 min at 25 degrees with 2 and 8 mM
G Valli et al.
Endocrinologia japonica, 39(6), 549-554 (1992-12-01)
Increasing evidence of the interaction of glucocorticoids and ovarian steroids prompted the current study. Effects of exogenously administered corticosterone acetate (3.5 mg/100 g b.w/day for one week) were examined on splenic nucleic acids, protein, lactate, and on lactate dehydrogenase (LDH)
Matthew N Hill et al.
European journal of pharmacology, 528(1-3), 99-102 (2005-12-06)
This research was designed to examine the effect of three weeks of administration of corticosterone (20 mg/kg) on endocannabinoid content and cannabinoid CB1 receptor binding in the amygdala. It was found that the endocannabinoid 2-arachidonylglycerol was significantly increased in the
B L Tepperman et al.
The American journal of physiology, 250(5 Pt 1), G617-G624 (1986-05-01)
Gastric mucosal responses to intraluminal instillation of acid (10, 50, and 150 mM HCl) and acidified solutions of sodium taurocholate (10 mM) were measured in rats between 5 and 60 days after birth. Net loss of H+ and gain of
A Gadek-Michalska et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 54(3), 449-459 (2003-10-21)
The purpose of the present study was to assess whether, and to what extent prior handling, restraint or social crowding stress during 3-10 days affects the hypothalamic-pituitary-adrenocortical (HPA) response to an acute short-lasting restraint stress. Also the effect of a
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